{"id":"W2917387482","doi":"10.1007/s11864-019-0617-6","title":"The Role of Angiogenesis Inhibitors in the Era of Immune Checkpoint Inhibitors and Targeted Therapy in Metastatic Non-Small Cell Lung Cancer","year":2019,"lang":"en","type":"review","venue":"Current Treatment Options in Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"Bristol-Myers Squibb","keywords":"Medicine; Bevacizumab; Oncology; Lung cancer; Atezolizumab; Anaplastic lymphoma kinase; Internal medicine; Population; Combination therapy; Targeted therapy; Chemotherapy; Maintenance therapy; Epidermal growth factor receptor; Immunotherapy; Cancer; Pembrolizumab; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000855771,0.000637739,0.001722046,0.001531769,0.0001845025,0.001198237,0.000850283,0.001062371,0.003788253],"category_scores_gemma":[0.001208831,0.0002313365,0.0007915044,0.001522825,0.0003661006,0.001328578,0.0006071048,0.002568996,0.001240782],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005749105,"about_ca_system_score_gemma":0.001016002,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009277349,"about_ca_topic_score_gemma":0.002665144,"domain_scores_codex":[0.9997737,0.00004540926,0.00003408081,0.00003411206,0.00008521394,0.00002756108],"domain_scores_gemma":[0.9994712,0.0003071262,0.00007894434,0.000009678096,0.00009740073,0.00003558966],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000168209,0.00006704019,0.0001099485,0.01699057,0.0001572754,0.0001085264,0.00003002498,0.0003908926,0.0009828347,0.002577357,0.02764801,0.9507693],"study_design_scores_gemma":[0.0001207365,0.0002514426,0.000846185,0.007318876,0.0004544985,0.0007391732,0.00004015756,0.0002152225,0.0004180899,0.002322328,0.9872473,0.00002601525],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006310966,0.9990948,0.00005587048,0.0002273195,0.0001302255,0.000002839432,0.0000164963,0.000003829136,0.0004054163],"genre_scores_gemma":[0.0004806904,0.9986565,0.0001126104,0.0003143645,0.0001473044,0.000004040363,0.0000258361,0.000001138757,0.00025746],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003788253,"threshold_uncertainty_score":0.01267302,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04126358621587533,"score_gpt":0.4020381611712739,"score_spread":0.3607745749553986,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}