{"id":"W2917568543","doi":"10.1007/s00262-018-02297-2","title":"Expression of a soluble IL-10 receptor enhances the therapeutic effects of a papillomavirus-associated antitumor vaccine in a murine model","year":2019,"lang":"en","type":"article","venue":"Cancer Immunology Immunotherapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Bureau of Reclamation; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Universidade de São Paulo; Fundação de Amparo à Pesquisa do Estado de São Paulo; International Centre for Genetic Engineering and Biotechnology","keywords":"Cytotoxic T cell; Adjuvant; DNA vaccination; CD8; Cancer research; Immunotherapy; Medicine; Immunology; Cancer immunotherapy; Immunization; Biology; Immune system; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004786872,0.001020147,0.000599485,0.0008617128,0.0002715929,0.0006658298,0.000437156,0.0009946579,0.001657757],"category_scores_gemma":[0.0003427978,0.0003511186,0.0005877589,0.0002244943,0.0006371569,0.0006975676,0.0002370245,0.003108126,0.0005364827],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006404314,"about_ca_system_score_gemma":0.0005133117,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009041844,"about_ca_topic_score_gemma":0.001036413,"domain_scores_codex":[0.9994513,0.0001134182,0.00004637377,0.00009262719,0.00009852894,0.0001976846],"domain_scores_gemma":[0.9994005,0.0001728351,0.0001344641,0.00009720482,0.00004534766,0.0001495753],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008926457,0.0009192597,0.0001265052,0.00004529162,0.00001033025,0.00007365992,0.00003039605,0.000344026,0.996119,0.0002749045,0.00009266643,0.001071325],"study_design_scores_gemma":[0.0001782557,0.003855665,0.0007576771,0.00001368925,0.00003761965,0.0001792385,0.00002782987,0.003031641,0.9908171,0.0001148117,0.0009780009,0.000008574702],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952873,0.0005825665,0.001940508,0.0002404947,0.000149038,0.0000809466,0.0002905881,0.0001325475,0.001296148],"genre_scores_gemma":[0.9937509,0.0004920791,0.001953643,0.00007742571,0.0000613852,0.00008268109,0.0003906252,0.00003620394,0.003155087],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001657757,"threshold_uncertainty_score":0.005545735,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009125941024972349,"score_gpt":0.2558850656372368,"score_spread":0.2467591246122645,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}