{"id":"W2917613065","doi":"10.1021/jacs.9b00862","title":"Coordination-Induced Stereocontrol over Carbocations: Asymmetric Reductive Deoxygenation of Racemic Tertiary Alcohols","year":2019,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Asymmetric Hydrogenation and Catalysis","field":"Chemistry","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Eidgenössische Technische Hochschule Zürich; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Chemistry; Carbocation; Enantioselective synthesis; Deoxygenation; Regioselectivity; Reductive elimination; Nucleophile; Moiety; Hydride; Combinatorial chemistry; Catalysis; Stereochemistry; Organic chemistry; Metal","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003236074,0.0004908118,0.0002425946,0.0001701673,0.0001523235,0.0003397849,0.0004729331,0.0002616926,0.001561946],"category_scores_gemma":[0.0003119246,0.0001436525,0.0002089542,0.0001803832,0.0004927248,0.0004035588,0.0004754888,0.0008427648,0.0004977965],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004337593,"about_ca_system_score_gemma":0.0003395194,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006754088,"about_ca_topic_score_gemma":0.001559528,"domain_scores_codex":[0.9997948,0.00002944623,0.00001575165,0.00004903133,0.00003819598,0.00007293763],"domain_scores_gemma":[0.9998894,0.00002147439,0.00003030939,0.00002741272,0.00001340694,0.00001810171],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001988886,0.00007830431,0.0003006005,0.0001463166,0.0000210536,0.0005505691,0.0002278487,0.001067618,0.9815777,0.004304828,0.0005067594,0.01101948],"study_design_scores_gemma":[0.00003075556,0.0001939003,0.0003443313,0.000004002314,0.000007849329,0.0002716399,0.00002656762,0.0005816986,0.9947247,0.0002478367,0.003555536,0.00001127411],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9444972,0.001496678,0.02716469,0.0004880993,0.0001207645,0.000171863,0.0005458674,0.0004134957,0.02510123],"genre_scores_gemma":[0.9948014,0.0005237109,0.002841313,0.00005017889,0.00001205733,0.0000149147,0.0001165334,0.00003771715,0.001602179],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001561946,"threshold_uncertainty_score":0.005225182,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007275976235981053,"score_gpt":0.251594538328048,"score_spread":0.2443185620920669,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}