{"id":"W2918002695","doi":"10.5376/cge.2018.06.0001","title":"Biomarker Alteration to Neoadjuvant Chemotherapy Predict Pathological Response and Prognosis in Breast Cancer Patients","year":2018,"lang":"en","type":"article","venue":"Cancer Genetics and Epigenetics","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Chemotherapy; Breast cancer; Oncology; Pathological; Internal medicine; Biomarker; Grading (engineering); Neoadjuvant therapy; Cancer; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003358822,0.0001853081,0.0002541777,0.0003597886,0.0001648672,0.000347762,0.0001295689,0.000253313,0.001202268],"category_scores_gemma":[0.001324077,0.00009450063,0.0002120236,0.0004134319,0.0001539286,0.0002199811,0.0001768247,0.0002918288,0.0002226461],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002108877,"about_ca_system_score_gemma":0.0001853105,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003683966,"about_ca_topic_score_gemma":0.0006559658,"domain_scores_codex":[0.9998173,0.00004509082,0.00002769384,0.00002738143,0.00004438803,0.00003825517],"domain_scores_gemma":[0.9994376,0.0001338227,0.0002387939,0.00002726544,0.00008052148,0.00008197942],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003432139,0.00003042614,0.9940338,0.00001820911,0.0000340226,0.00008890816,0.00002336701,0.00008322683,0.001219723,0.00001205609,0.0000982005,0.00401485],"study_design_scores_gemma":[0.000009795651,0.0001983239,0.9968894,0.00001037247,0.00005944868,0.0006416586,0.00008166473,0.000469746,0.0008552136,0.00006669585,0.0007133955,0.000004304181],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982731,0.0009241615,0.0001257422,0.00006284511,0.00001460169,0.000008007128,0.0001334971,0.000003645407,0.0004543981],"genre_scores_gemma":[0.9993075,0.0001572434,0.0001269012,0.00002247621,0.00001211951,0.0000104894,0.0002015813,9.062207e-7,0.0001608087],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001202268,"threshold_uncertainty_score":0.004021943,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01213120860409769,"score_gpt":0.283408110338741,"score_spread":0.2712769017346433,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}