{"id":"W2918002695","doi":"10.5376/cge.2018.06.0001","title":"Biomarker Alteration to Neoadjuvant Chemotherapy Predict Pathological Response and Prognosis in Breast Cancer Patients","year":2018,"lang":"en","type":"article","venue":"Cancer Genetics and Epigenetics","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Chemotherapy; Breast cancer; Oncology; Pathological; Internal medicine; Biomarker; Grading (engineering); Neoadjuvant therapy; Cancer; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001330524,0.0002563587,0.0002115668,0.00007195323,0.0001206887,0.00004261221,0.0001006625,0.0001504003,0.00002247835],"category_scores_gemma":[0.00001993399,0.0002276079,0.00003093022,0.0001474061,0.0002245995,0.000003915822,0.0001659372,0.00005360635,0.000001690887],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005228341,"about_ca_system_score_gemma":0.00007335476,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000874114,"about_ca_topic_score_gemma":0.0003068403,"domain_scores_codex":[0.9985923,0.00008030482,0.000255752,0.0005831052,0.0001411604,0.000347359],"domain_scores_gemma":[0.9993674,0.00001501398,0.00006795052,0.0001960859,0.0001912687,0.000162344],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001336814,0.0001299337,0.8821333,0.00001487571,0.00006212001,0.00000217631,0.0004457858,0.00003227546,0.03519215,0.000001857339,0.0007794118,0.07986929],"study_design_scores_gemma":[0.001398558,0.0006191635,0.9671122,0.00004914567,0.00003139451,0.000006320594,0.00003400982,0.0001713917,0.02490301,0.00002492144,0.005382695,0.0002672092],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923608,0.004436782,0.0001458156,0.002031734,0.0002225125,0.0004370835,0.0003358647,0.0000100928,0.00001927915],"genre_scores_gemma":[0.9831275,0.01449223,0.0007030214,0.001016326,0.0002952746,0.0002666806,0.00002863295,0.00003426874,0.0000360603],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08497886,"threshold_uncertainty_score":0.9281581,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01213120860409769,"score_gpt":0.283408110338741,"score_spread":0.2712769017346433,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}