{"id":"W2918027232","doi":"10.3390/genes10030183","title":"Progression of Cystic Fibrosis Lung Disease from Childhood to Adulthood: Neutrophils, Neutrophil Extracellular Trap (NET) Formation, and NET Degradation","year":2019,"lang":"en","type":"review","venue":"Genes","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":114,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Mitacs; Cystic Fibrosis Canada","keywords":"Neutrophil extracellular traps; Cystic fibrosis; Immunology; Mucus; Lung; Inflammation; Cystic fibrosis transmembrane conductance regulator; Medicine; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001783514,0.000724644,0.001681401,0.0003708784,0.0002184787,0.00005037385,0.0004377576,0.0005088333,0.0001563925],"category_scores_gemma":[0.00004277821,0.0005712605,0.0003750423,0.0003288513,0.00009715597,0.0002509168,0.000234648,0.000367036,0.0002619719],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006483111,"about_ca_system_score_gemma":0.0001948647,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002293393,"about_ca_topic_score_gemma":0.000003044391,"domain_scores_codex":[0.996923,0.0005943423,0.001012657,0.000850954,0.0001237431,0.0004953287],"domain_scores_gemma":[0.9980903,0.0001876732,0.000703147,0.0007419581,0.0001364818,0.0001404083],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001876556,0.0002443424,0.00003350213,0.007083769,0.0004269019,0.00001622241,0.0002983118,0.000009734041,0.03722006,0.0004128617,0.0006516802,0.953415],"study_design_scores_gemma":[0.002034092,0.0008380499,0.001405791,0.01731944,0.004757843,0.00008064535,0.0001192695,0.00001804999,0.02489071,0.0002068339,0.9466807,0.001648634],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01882231,0.9759156,0.001045489,0.00006795819,0.00059493,0.002288095,0.001184458,0.0000739898,0.00000712767],"genre_scores_gemma":[0.004452503,0.9874902,0.0009479711,0.00005837894,0.0001781178,0.0002916205,0.006290711,0.0001008802,0.0001895664],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9517663,"threshold_uncertainty_score":0.9996739,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02103033884428994,"score_gpt":0.2731787409728529,"score_spread":0.252148402128563,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}