{"id":"W2918180482","doi":"10.1111/hiv.12716","title":"Two‐drug <i>vs</i>. three‐drug combinations for <scp>HIV</scp>‐1: Do we have enough data to make the switch?","year":2019,"lang":"en","type":"review","venue":"HIV Medicine","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"Cilag; ViiV Healthcare; Gilead Sciences; Pfizer; Bristol-Myers Squibb","keywords":"Medicine; Drug; Regimen; Adverse effect; Viral load; Pharmacology; Drug resistance; Pill; Combination therapy; HIV drug resistance; Human immunodeficiency virus (HIV); Intensive care medicine; Antiretroviral therapy; Immunology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002131566,0.0003020263,0.001009065,0.0003683218,0.0002433008,0.001777556,0.0006232609,0.001339486,0.01355467],"category_scores_gemma":[0.002558945,0.0001314197,0.001052844,0.0003682302,0.0008395995,0.002308323,0.0004012628,0.002717342,0.002645828],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006017298,"about_ca_system_score_gemma":0.0006150315,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006312612,"about_ca_topic_score_gemma":0.00268013,"domain_scores_codex":[0.9992239,0.0003877683,0.00006346306,0.00009442307,0.0001598754,0.00007049511],"domain_scores_gemma":[0.9982792,0.000907873,0.0003224344,0.00008039502,0.0001676599,0.0002424145],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01017021,0.0004404634,0.001414445,0.0044011,0.0003516989,0.0002304701,0.0001068055,0.0002009481,0.001873165,0.008166919,0.04426384,0.92838],"study_design_scores_gemma":[0.009367524,0.01888059,0.01210903,0.0101383,0.002073756,0.003458451,0.001029848,0.001665565,0.003328431,0.0230152,0.9147224,0.0002109377],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.04436515,0.8363764,0.001866374,0.08046072,0.01014944,0.0001626087,0.0005037447,0.000175698,0.0259399],"genre_scores_gemma":[0.3434664,0.5184923,0.007972463,0.09239955,0.01609768,0.0003432642,0.0009448903,0.0002148732,0.02006856],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01355467,"threshold_uncertainty_score":0.04534489,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1112295242288524,"score_gpt":0.3698249872706382,"score_spread":0.2585954630417858,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}