{"id":"W2918228238","doi":"10.1016/j.bioorg.2019.02.038","title":"Hollow silica microspheres as robust immobilization carriers","year":2019,"lang":"en","type":"article","venue":"Bioorganic Chemistry","topic":"Enzyme Catalysis and Immobilization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke; Materium Innovations (Canada)","funders":"Narodowym Centrum Nauki","keywords":"Glutaraldehyde; Chemistry; Immobilized enzyme; Covalent bond; Surface modification; Aqueous solution; Biocatalysis; Lipase; Ethylbenzene; Combinatorial chemistry; Organic chemistry; Enzyme; Amine gas treating; Chemical engineering; Polymer chemistry; Catalysis; Reaction mechanism","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00008833403,0.0001966688,0.0001588149,0.00001068491,0.00006309112,0.00004181885,0.0002393877,0.0002681857,0.001332809],"category_scores_gemma":[0.0001089918,0.0002001351,0.0001162412,0.0001836288,0.00005808242,0.000006909786,0.0001067073,0.00008006561,0.0001840584],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003855759,"about_ca_system_score_gemma":0.0001339293,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001520235,"about_ca_topic_score_gemma":0.000005130143,"domain_scores_codex":[0.9988663,0.00001559473,0.0002238241,0.0005192577,0.0001411936,0.0002338508],"domain_scores_gemma":[0.9990754,0.000006023547,0.0001038192,0.0006105684,0.0001064617,0.00009770934],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002534735,0.00004160711,0.003440936,0.00004922495,0.00004012934,6.652003e-7,0.00002123282,0.00009740852,0.9922676,0.000006521011,0.003868631,0.0001406975],"study_design_scores_gemma":[0.0004370372,0.00005492796,0.0004549562,0.00001372352,0.00002171394,0.00001707085,0.0002105963,0.00004840048,0.9659903,0.000006781606,0.03249401,0.000250497],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928027,0.001023498,0.0001287597,0.00004541954,0.000110266,0.0001692235,0.00001470519,0.00003319011,0.005672192],"genre_scores_gemma":[0.9837001,0.0001462904,0.00009064825,0.0001774068,0.0001913376,0.00001178163,0.0009507987,0.00004423411,0.01468743],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02862538,"threshold_uncertainty_score":0.9995801,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004929871823628235,"score_gpt":0.2046747214145273,"score_spread":0.1997448495908991,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}