{"id":"W2918529223","doi":"10.1016/j.humimm.2019.03.001","title":"Next-generation HLA typing of 382 International Histocompatibility Working Group reference B-lymphoblastoid cell lines: Report from the 17th International HLA and Immunogenetics Workshop","year":2019,"lang":"en","type":"article","venue":"Human Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University and Génome Québec Innovation Centre; McGill University Health Centre","funders":"National Institutes of Health; Kuwait Foundation for the Advancement of Sciences; National Institute of Neurological Disorders and Stroke; Kuwait University; Rijksdienst voor Ondernemend Nederland","keywords":"Human leukocyte antigen; Concordance; Genotyping; Typing; Biology; Immunogenetics; Genetics; Genotype; Allele; Allotype; HLA-B; HLA-B Antigens; Histocompatibility; Gene; Computational biology; Antigen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002199573,0.0005049266,0.0004757366,0.0009186984,0.0004510947,0.0008224047,0.0006142775,0.0005515647,0.002344013],"category_scores_gemma":[0.001552562,0.0002393407,0.0005566831,0.0006804655,0.0003029477,0.000244546,0.0005649897,0.001069668,0.001158167],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002980437,"about_ca_system_score_gemma":0.0004430218,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003123478,"about_ca_topic_score_gemma":0.004573619,"domain_scores_codex":[0.9994573,0.0001705125,0.00005696777,0.00007675435,0.0001563944,0.00008201333],"domain_scores_gemma":[0.998522,0.0006113317,0.00005441247,0.0002908699,0.0003416029,0.000179766],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001416146,0.0003891028,0.02549871,0.0001707648,0.0001402053,0.0005995524,0.0006750148,0.0005058942,0.9087538,0.000640169,0.00596244,0.05524837],"study_design_scores_gemma":[0.0004992849,0.00224554,0.2185241,0.0001118181,0.0008208141,0.0031189,0.0007904725,0.003327756,0.6364505,0.001655648,0.1323776,0.00007749882],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.92867,0.007677871,0.0408209,0.001372478,0.0004515824,0.000620321,0.01054472,0.0002508265,0.009591295],"genre_scores_gemma":[0.8613702,0.006669057,0.06208608,0.001336662,0.0001974908,0.0009208912,0.05484235,0.0002467484,0.01233066],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003123478,"threshold_uncertainty_score":0.01163262,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04608327378378587,"score_gpt":0.256462386077413,"score_spread":0.2103791122936271,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}