{"id":"W2918578802","doi":"10.3389/fnmol.2019.00041","title":"The Dietary Flavonoid, Luteolin, Negatively Affects Neuronal Differentiation","year":2019,"lang":"en","type":"article","venue":"Frontiers in Molecular Neuroscience","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research; Department of Science and Technology, Ministry of Science and Technology, India; Jawaharlal Nehru Centre for Advanced Scientific Research; Council of Scientific and Industrial Research, India; Department of Biotechnology, Ministry of Science and Technology, India","keywords":"Luteolin; Apigenin; Neurite; Neuroprotection; Neurotoxicity; Cellular differentiation; Cell biology; Embryonic stem cell; Biology; Flavonoid; Pharmacology; Chemistry; Biochemistry; Antioxidant; In vitro; Toxicity","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006157052,0.0002012047,0.0001700956,0.000179515,0.0001046626,0.0001530783,0.0001332765,0.0002121209,0.0006808456],"category_scores_gemma":[0.0001015777,0.00007890866,0.0001663262,0.00007034739,0.0001620389,0.000172484,0.0001109256,0.0003429269,0.0001247038],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002781689,"about_ca_system_score_gemma":0.0001952176,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009899249,"about_ca_topic_score_gemma":0.001675284,"domain_scores_codex":[0.9999422,0.000007792009,0.00000660747,0.00001521176,0.00001524893,0.00001302155],"domain_scores_gemma":[0.9999388,0.00001306294,0.00001663808,0.000005361126,0.000009758975,0.00001623013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009705083,0.00001141855,0.0001032995,0.00002457715,0.00000217255,0.00002166053,0.000006291662,0.00001067501,0.9988513,0.00002845862,0.00002140619,0.0008216897],"study_design_scores_gemma":[0.00001198927,0.0002169329,0.004951827,0.000005168575,0.00001353384,0.00008917294,0.00001657116,0.0001968641,0.9927869,0.00005259593,0.001654907,0.000003510365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943427,0.001932141,0.001529664,0.0001326533,0.00002943403,0.00001464728,0.0003339908,0.00007282151,0.001612129],"genre_scores_gemma":[0.9945623,0.001226977,0.001421335,0.00006627588,0.000005809243,0.00002243614,0.0002881958,0.00001941275,0.002387224],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009899249,"threshold_uncertainty_score":0.002277613,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01259671915716375,"score_gpt":0.222735833181952,"score_spread":0.2101391140247882,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}