{"id":"W2919081889","doi":"10.1016/j.jpain.2019.02.010","title":"Perioperative Pregabalin and Intraoperative Lidocaine Infusion to Reduce Persistent Neuropathic Pain After Breast Cancer Surgery: A Multicenter, Factorial, Randomized, Controlled Pilot Trial","year":2019,"lang":"en","type":"article","venue":"Journal of Pain","topic":"Anesthesia and Pain Management","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":false,"ca_institutions":"York University; Population Health Research Institute; McMaster University; Queen's University; Impact; Sunnybrook Health Science Centre; Toronto General Hospital; University Health Network; University of Toronto","funders":"Canadian Institutes of Health Research; York University; Abbott Diagnostics; Physicians' Services Incorporated Foundation; Health Psychology; McMaster University; Boehringer Ingelheim; Philips Oral Healthcare; AstraZeneca Canada; Health Research; University of Toronto; GlaxoSmithKline","keywords":"Medicine; Pregabalin; Perioperative; Anesthesia; Lidocaine; Placebo; Neuropathic pain; Randomized controlled trial; Breast cancer; Surgery; Breast surgery; Cancer; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01997654,0.0003040044,0.00202216,0.0002824704,0.00007076804,0.00009812235,0.00008705334,0.00007569399,0.0004495356],"category_scores_gemma":[0.003568801,0.0001842876,0.0006097649,0.0001485293,0.00008246722,0.0001499527,0.00003447559,0.0003613853,0.000009401531],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001510076,"about_ca_system_score_gemma":0.0002533347,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007258353,"about_ca_topic_score_gemma":0.00001339802,"domain_scores_codex":[0.990477,0.007365125,0.00107332,0.0002715372,0.0005346503,0.0002783734],"domain_scores_gemma":[0.9952012,0.003348622,0.0005024258,0.0001741232,0.0004609332,0.0003127257],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9799732,0.0004725753,0.0070302,0.0001226765,0.0006705828,0.0002830349,0.00395446,0.00008489189,0.002536214,0.00001304603,0.001234971,0.003624169],"study_design_scores_gemma":[0.9712907,0.005433213,0.003902042,0.001950563,0.0009821383,0.0001718293,0.002046572,0.008927733,0.00006882322,0.000004518649,0.004865993,0.0003558942],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.980355,0.0009824631,0.001282759,0.0118758,0.0006940327,0.004749976,0.00000428785,0.00001317915,0.00004247144],"genre_scores_gemma":[0.9908211,0.0005474278,0.0001607164,0.006072735,0.001171699,0.0001866908,0.00000263018,0.00003026424,0.001006717],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01640774,"threshold_uncertainty_score":0.751503,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0143544733001718,"score_gpt":0.2649878396484343,"score_spread":0.2506333663482624,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}