{"id":"W2919081889","doi":"10.1016/j.jpain.2019.02.010","title":"Perioperative Pregabalin and Intraoperative Lidocaine Infusion to Reduce Persistent Neuropathic Pain After Breast Cancer Surgery: A Multicenter, Factorial, Randomized, Controlled Pilot Trial","year":2019,"lang":"en","type":"article","venue":"Journal of Pain","topic":"Anesthesia and Pain Management","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":false,"ca_institutions":"York University; Population Health Research Institute; McMaster University; Queen's University; Impact; Sunnybrook Health Science Centre; Toronto General Hospital; University Health Network; University of Toronto","funders":"Canadian Institutes of Health Research; York University; Abbott Diagnostics; Physicians' Services Incorporated Foundation; Health Psychology; McMaster University; Boehringer Ingelheim; Philips Oral Healthcare; AstraZeneca Canada; Health Research; University of Toronto; GlaxoSmithKline","keywords":"Medicine; Pregabalin; Perioperative; Anesthesia; Lidocaine; Placebo; Neuropathic pain; Randomized controlled trial; Breast cancer; Surgery; Breast surgery; Cancer; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001922736,0.001796242,0.004169896,0.0004261094,0.0006385871,0.001215754,0.001214527,0.001760549,0.004564062],"category_scores_gemma":[0.00305765,0.0009275348,0.001846194,0.0005630702,0.001809676,0.001311895,0.0005885146,0.003051703,0.000640331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007827235,"about_ca_system_score_gemma":0.00171671,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001422786,"about_ca_topic_score_gemma":0.002090017,"domain_scores_codex":[0.9987785,0.0005916931,0.0001226299,0.0002283056,0.00009499584,0.0001837968],"domain_scores_gemma":[0.9981921,0.0006922719,0.0004144048,0.0001501608,0.0001270817,0.0004238496],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9858962,0.006503443,0.00020426,0.0003612617,0.0006546535,0.00001390542,0.00003264387,0.0001007236,0.001114952,0.00004947978,0.0001457527,0.004922713],"study_design_scores_gemma":[0.9303246,0.06773101,0.0007780783,0.00002796011,0.0005892663,0.00001088267,0.00002021706,0.000166489,0.0001896053,0.00004715464,0.0001041509,0.00001071845],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909416,0.00346993,0.000687605,0.0003873662,0.0005634399,0.00282287,0.0003695656,0.00006226427,0.0006953173],"genre_scores_gemma":[0.9864803,0.003035186,0.002406782,0.0006406257,0.0006921146,0.005126939,0.0004081407,0.00002243418,0.001187534],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004564062,"threshold_uncertainty_score":0.01526839,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0143544733001718,"score_gpt":0.2649878396484343,"score_spread":0.2506333663482624,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}