{"id":"W2919145100","doi":"10.1186/s13046-019-1032-3","title":"PAGE4 promotes prostate cancer cells survive under oxidative stress through modulating MAPK/JNK/ERK pathway","year":2019,"lang":"en","type":"article","venue":"Journal of Experimental & Clinical Cancer Research","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Natural Science Foundation of China; Canada Millennium Scholarship Foundation","keywords":"MAPK/ERK pathway; Oxidative stress; Prostate cancer; Cancer research; Apoptosis; Cell biology; Chemistry; Cancer; Medicine; Signal transduction; Biology; Internal medicine; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001321814,0.0004032724,0.0003181924,0.0003664339,0.0002697061,0.0003148885,0.0001992439,0.0002598884,0.002557937],"category_scores_gemma":[0.0001213767,0.0001153308,0.0005824097,0.0002593587,0.0002208585,0.0002889666,0.0002424343,0.0006988009,0.0004771493],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002208834,"about_ca_system_score_gemma":0.0003818386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003083742,"about_ca_topic_score_gemma":0.0005130515,"domain_scores_codex":[0.9998831,0.00001813013,0.000008595851,0.00001991458,0.00003429913,0.0000359249],"domain_scores_gemma":[0.9999228,0.000006695397,0.00002189319,0.000005340969,0.00002352208,0.00001983128],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001100872,0.0002280413,0.00356618,0.001124444,0.00007576557,0.0003092168,0.00005641846,0.0003023141,0.9814281,0.0002763203,0.0008828574,0.01064924],"study_design_scores_gemma":[0.00009909042,0.001764531,0.04378754,0.00006963995,0.0002122486,0.001380536,0.0001885583,0.00182957,0.9366095,0.0005544838,0.01347766,0.00002677048],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9662743,0.02173,0.005426726,0.0007335958,0.0002262915,0.0000793563,0.001322938,0.0003079071,0.003898958],"genre_scores_gemma":[0.9854187,0.007475034,0.002044162,0.0001613024,0.00005383661,0.00007347758,0.00119467,0.00002261783,0.003556271],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002557937,"threshold_uncertainty_score":0.008557141,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1261427868304989,"score_gpt":0.4715424035034527,"score_spread":0.3453996166729538,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}