{"id":"W2919341381","doi":"10.1016/j.jtos.2019.02.012","title":"Efficacy of topical ophthalmic drugs in the treatment of dry eye disease: A systematic literature review","year":2019,"lang":"en","type":"review","venue":"The Ocular Surface","topic":"Ocular Surface and Contact Lens","field":"Medicine","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo; McGill University","funders":"VISTAKON Pharmaceuticals; Natural Sciences and Engineering Research Council of Canada; Allergan; Alcon; Canadian Institutes of Health Research; Novartis; Santen; CooperVision; Shire; National Institutes of Health","keywords":"Medicine; Clinical trial; Clinical endpoint; Adverse effect; Disease; Drug; Clinical study design; Intensive care medicine; Internal medicine; Pharmacology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007766921,0.0005171699,0.003766902,0.00006466286,0.00003097518,0.00001797045,0.0005488609,0.0002075952,0.00002943741],"category_scores_gemma":[0.0001267593,0.0002201869,0.00171583,0.0006427624,0.00007684556,0.00003201185,0.00004689861,0.0003621221,0.00007541775],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001375991,"about_ca_system_score_gemma":0.0003472027,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001362334,"about_ca_topic_score_gemma":0.000001223661,"domain_scores_codex":[0.9962112,0.001407536,0.001111401,0.0003709723,0.0006238183,0.0002750587],"domain_scores_gemma":[0.9963749,0.0005907491,0.0005826064,0.002283475,0.00008555278,0.00008269638],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","study_design_scores_codex":[0.00004222279,0.0006138947,0.0005609761,0.9868703,0.0007234918,0.0001825631,0.001082425,0.000002478552,0.000002261976,0.0001684628,0.000008604415,0.009742352],"study_design_scores_gemma":[0.0007923894,0.0003159279,0.000458251,0.8640472,0.01128225,0.00001153352,0.00009870883,0.000008167263,0.000003602751,0.000005297809,0.1227423,0.0002344495],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006274404,0.9856578,0.000001678717,0.0002656675,0.0001081743,0.007435837,0.00004493285,0.00001220912,0.0001993632],"genre_scores_gemma":[0.0008568153,0.9974216,0.00003516532,0.00007702471,0.00004560747,0.000103372,0.0001191317,0.00004885747,0.001292441],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.1228231,"threshold_uncertainty_score":0.8978963,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02933807032768836,"score_gpt":0.3387704185972495,"score_spread":0.3094323482695612,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}