{"id":"W2919879111","doi":"10.1039/c8sm02315h","title":"Controlled generation of spiky microparticles by ionic cross-linking within an aqueous two-phase system","year":2019,"lang":"en","type":"article","venue":"Soft Matter","topic":"Innovative Microfluidic and Catalytic Techniques Innovation","field":"Engineering","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Metropolitan University; Toronto Public Health; St. Michael's Hospital","funders":"Natural Sciences and Engineering Research Council of Canada; Ontario Ministry of Research, Innovation and Science","keywords":"Microparticle; Polyethylene glycol; Drug delivery; Aqueous solution; Chemical engineering; Nanotechnology; Aqueous two-phase system; Phase (matter); Ionic bonding; PEG ratio; Materials science; Dextran; Biocompatible material; Chemistry; Chromatography; Biomedical engineering; Organic chemistry; Ion","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001987464,0.0002693199,0.0001457468,0.0001964026,0.0001159012,0.0002515012,0.0001611141,0.0002705232,0.0002999991],"category_scores_gemma":[0.0001785426,0.0001398933,0.0001688565,0.0001186978,0.0002185753,0.0002452886,0.0002673538,0.0003463662,0.0001820509],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002035488,"about_ca_system_score_gemma":0.0001655752,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001373236,"about_ca_topic_score_gemma":0.0003103142,"domain_scores_codex":[0.9998878,0.0000110496,0.00001450845,0.00003656695,0.00003132777,0.0000186173],"domain_scores_gemma":[0.9998561,0.00003107694,0.00006487611,0.00001160284,0.00001438924,0.00002195921],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000009993303,0.00000624549,0.00003383255,0.00001193553,0.000001238845,0.00001181189,0.000006171916,0.0000604607,0.9992043,0.00004431777,0.00001126525,0.0005984517],"study_design_scores_gemma":[0.000005556612,0.00007151566,0.0002634777,0.000001384697,0.000003333731,0.00003086434,0.000003609404,0.001067032,0.9979433,0.00001389184,0.0005928099,0.000003193104],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9657695,0.0005758718,0.0319712,0.000128835,0.00003948463,0.0001263787,0.0001619128,0.0002044428,0.001022291],"genre_scores_gemma":[0.9672852,0.000475637,0.03057212,0.0000833816,0.00001890264,0.00007748951,0.0001377698,0.00004815078,0.00130124],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0002999991,"threshold_uncertainty_score":0.001476884,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01235033317306967,"score_gpt":0.2656168956993893,"score_spread":0.2532665625263197,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}