{"id":"W2920358651","doi":"10.3389/fmicb.2019.00127","title":"The Selection of a Hepatocyte Cell Line Susceptible to Plasmodium falciparum Sporozoite Invasion That Is Associated With Expression of Glypican-3","year":2019,"lang":"en","type":"article","venue":"Frontiers in Microbiology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Office of Extramural Research, National Institutes of Health; National Center for Research Resources; Emerging Pathogens Institute, University of Florida; National Institutes of Health; York University; Bloomberg Family Foundation; Villum Fonden; National Institute of Allergy and Infectious Diseases; Division of Intramural Research, National Institute of Allergy and Infectious Diseases; Johns Hopkins University; University of Florida","keywords":"Plasmodium falciparum; Glypican 3; Biology; Selection (genetic algorithm); Hepatocyte; Cell culture; Cell biology; Plasmodium (life cycle); Virology; Malaria; Immunology; Genetics; In vitro; Immunohistochemistry; Parasite hosting; Computer science","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003422378,0.0002545289,0.0003142396,0.0002147405,0.0003534455,0.0003911123,0.0001961551,0.0002275655,0.001720846],"category_scores_gemma":[0.0002299393,0.0002090192,0.000250151,0.0002996041,0.0001816237,0.0001441119,0.0003117203,0.0005072876,0.001097588],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002042421,"about_ca_system_score_gemma":0.0002505506,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001620902,"about_ca_topic_score_gemma":0.003014118,"domain_scores_codex":[0.9995551,0.0001038247,0.00005685334,0.0000728981,0.0001519163,0.00005944727],"domain_scores_gemma":[0.9997274,0.00006670335,0.00003924535,0.00006056382,0.00006063352,0.00004539301],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006671325,0.00003175651,0.0004869283,0.00002956782,0.000003956244,0.00007240274,0.00003909957,0.00005945347,0.9982827,0.0001117998,0.0001194893,0.0006962589],"study_design_scores_gemma":[0.00002046124,0.0002870677,0.008446093,0.000007996026,0.00002443051,0.0006076882,0.00009362806,0.002490373,0.9810323,0.00004634541,0.006927166,0.00001647437],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9627868,0.0007508483,0.02688877,0.0002831021,0.00008446101,0.0003537425,0.002826801,0.000277081,0.005748373],"genre_scores_gemma":[0.9549323,0.0008674146,0.02616313,0.0001971577,0.00002504677,0.0004681835,0.005143128,0.0001454896,0.01205805],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001720846,"threshold_uncertainty_score":0.005756795,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00811901000651782,"score_gpt":0.2101341456548775,"score_spread":0.2020151356483596,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}