{"id":"W2920693110","doi":"10.1093/carcin/bgz042","title":"XB130 deficiency enhances carcinogen-induced skin tumorigenesis","year":2019,"lang":"en","type":"article","venue":"Carcinogenesis","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research","keywords":"Carcinogenesis; DMBA; Cancer research; Oncogene; Biology; Cancer; Cell cycle; Internal medicine; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001287323,0.0003163081,0.0002832742,0.00008520934,0.0001249312,0.0000421302,0.0004022219,0.0001679008,0.0002263685],"category_scores_gemma":[0.00005527556,0.0002929206,0.0002771113,0.0002063393,0.00006122822,0.000007597543,0.0001580248,0.0000654631,0.0002783299],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002849606,"about_ca_system_score_gemma":0.0001788942,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001195732,"about_ca_topic_score_gemma":0.00003018136,"domain_scores_codex":[0.9980254,0.00008036137,0.000303704,0.0007632061,0.0003001553,0.0005271354],"domain_scores_gemma":[0.9986697,0.00001997799,0.0001092223,0.0008218657,0.0001367192,0.0002425231],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005699653,0.00006520166,0.1812247,0.00005526237,0.00002728906,0.0000102318,0.0000458445,0.00004722107,0.8165839,0.00009039489,0.0003284208,0.001464552],"study_design_scores_gemma":[0.0005331255,0.0002151297,0.1142094,0.00001310555,0.00005297211,0.00001835907,0.0002584074,0.00003529895,0.8823263,0.00002364135,0.001907801,0.0004064459],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990429,0.003333,0.00008289584,0.00004530016,0.0005303071,0.0003322906,0.00004408836,0.00003424086,0.005168886],"genre_scores_gemma":[0.9979251,0.0002934005,0.0001375271,0.0002371564,0.0002831877,0.00006706855,0.0000950018,0.00005220312,0.0009093344],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06701532,"threshold_uncertainty_score":0.9999523,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007394635913396522,"score_gpt":0.2287634888771047,"score_spread":0.2213688529637082,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}