{"id":"W2920757318","doi":"10.1038/s41598-019-40136-1","title":"Vegfa/vegfr2 signaling is necessary for zebrafish islet vessel development, but is dispensable for beta-cell and alpha-cell formation","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Vanderbilt University","keywords":"Zebrafish; Islet; Cell biology; Beta cell; BETA (programming language); Alpha cell; Vascular endothelial growth factor A; Alpha (finance); Endothelial stem cell; Biology; Gene knockdown; Kinase insert domain receptor; Cell; Pancreatic islets; Chemistry; VEGF receptors; Vascular endothelial growth factor; Cell culture; Cancer research; Endocrinology; Insulin; Medicine; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001766191,0.0003632779,0.0002765215,0.0003150747,0.0002306938,0.0003766679,0.0002196598,0.0003247441,0.002651521],"category_scores_gemma":[0.0002190641,0.0003143612,0.0002877032,0.0001167921,0.0003076838,0.0003737103,0.0002773312,0.0007016784,0.0007641952],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005398431,"about_ca_system_score_gemma":0.0005168809,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003004463,"about_ca_topic_score_gemma":0.004711059,"domain_scores_codex":[0.9997372,0.00002148886,0.00002391318,0.00006892428,0.00009024123,0.00005815542],"domain_scores_gemma":[0.9996892,0.00004140817,0.0001145968,0.00002451849,0.00003286401,0.00009729357],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003129192,0.000003934182,0.0001248747,0.00001519399,0.000001368677,0.00005393117,0.000008128819,0.00002152899,0.9991048,0.00008635907,0.00003121493,0.0005174053],"study_design_scores_gemma":[0.00002755699,0.0001151459,0.01116273,0.00001606104,0.00001862754,0.0004447723,0.00004247507,0.001031265,0.9826298,0.00008098106,0.0044211,0.000009563724],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9846822,0.002004321,0.005864877,0.0002076368,0.00005996414,0.00002936953,0.00103449,0.0003320549,0.005785148],"genre_scores_gemma":[0.9896353,0.0005212224,0.003249453,0.00006888936,0.00001030871,0.0000484208,0.0006051056,0.00009944658,0.005761917],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003004463,"threshold_uncertainty_score":0.008870184,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01972485039214764,"score_gpt":0.2461849216679378,"score_spread":0.2264600712757902,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}