{"id":"W2920825383","doi":"10.1161/atvb.38.suppl_1.669","title":"Abstract 669: Apabetalone (rvx-208) Decreases Risk of Major Adverse Cardiovascular Events in Diabetes Mellitus Patients With Cvd by Attenuating Monocyte Adhesion to Endothelial Cells","year":2018,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Resverlogix (Canada)","funders":"","keywords":"Bromodomain; Farnesoid X receptor; Chemistry; Epigenetics; Endocrinology; Internal medicine; Acetylation; Monocyte; Biochemistry; Biology; Gene; Medicine; Transcription factor; Nuclear receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006148709,0.0003288005,0.00034496,0.0001316741,0.00007878039,0.0001309417,0.0001412542,0.0002618261,0.0030049],"category_scores_gemma":[0.00008320926,0.00009640457,0.0001578778,0.0001068428,0.00008298477,0.00007506702,0.0001044553,0.0004357004,0.0005303184],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007302781,"about_ca_system_score_gemma":0.0001218758,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004015503,"about_ca_topic_score_gemma":0.000435489,"domain_scores_codex":[0.999966,0.000008522005,0.000003889343,0.000005972,0.000006506104,0.000008971791],"domain_scores_gemma":[0.9999561,0.00000470557,0.00001255513,0.000002632428,0.000005497534,0.0000185011],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.01797428,0.001669212,0.002495941,0.0003702973,0.00009022152,0.0001674299,0.00001779078,0.0001329174,0.9408964,0.00005376702,0.0005686698,0.03556313],"study_design_scores_gemma":[0.007161952,0.07811795,0.1257292,0.00009851036,0.0004974818,0.001267555,0.0000843637,0.001168446,0.7764394,0.0001174791,0.009292091,0.00002564697],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995097,0.002754516,0.0004286531,0.0001182443,0.00007020824,0.00004495483,0.0004264598,0.0000890368,0.0009708707],"genre_scores_gemma":[0.9932807,0.001670958,0.001049534,0.0001462588,0.0000536331,0.00004088562,0.0006964401,0.000009498465,0.003052123],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0030049,"threshold_uncertainty_score":0.01005244,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01901908865257857,"score_gpt":0.2341412838902946,"score_spread":0.215122195237716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}