{"id":"W2920828029","doi":"10.1167/iovs.18-25347","title":"Electrophysiological Changes During Early Steps of Retinitis Pigmentosa","year":2019,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Foundation Fighting Blindness","keywords":"Visual phototransduction; Rhodopsin; Retinitis pigmentosa; Retinal degeneration; Retinal; Retina; Xenopus; Biology; Electrophysiology; Electroretinography; Erg; Photoreceptor cell; Anatomy; Neuroscience; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002518969,0.0001658895,0.0001946042,0.0000890088,0.0001200401,0.00001555673,0.000387206,0.0001164072,0.0001000182],"category_scores_gemma":[0.0001810894,0.0001441332,0.00004765678,0.0003821655,0.001817536,0.00001252478,0.0002719201,0.0001064543,0.00003912272],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001894401,"about_ca_system_score_gemma":0.0001585858,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002521022,"about_ca_topic_score_gemma":0.000001968888,"domain_scores_codex":[0.9985033,0.00009582548,0.0001832519,0.0005478987,0.0002468946,0.0004228589],"domain_scores_gemma":[0.9994023,0.00002041595,0.000142816,0.0001921654,0.0001163487,0.0001259433],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008775285,0.00003615918,0.1045553,0.0000117839,0.00001104643,0.00000553896,0.00008819117,0.000002917002,0.8950594,0.00007230995,0.000005913578,0.00006369448],"study_design_scores_gemma":[0.000173063,0.001448034,0.3951175,0.00001147759,0.000002372303,0.00001880747,0.00005657478,0.000003944027,0.6024918,0.0005306196,0.00002842463,0.0001173814],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955128,0.00007387051,8.322189e-7,0.000100574,0.0001190238,0.00022024,0.000003235924,0.000009051879,0.003960314],"genre_scores_gemma":[0.9989607,0.00003081115,0.0003657872,0.0000710706,0.00003901225,0.00001936372,0.0000126932,0.000009256818,0.0004913428],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2925676,"threshold_uncertainty_score":0.6696786,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01745486171758119,"score_gpt":0.2867000129916631,"score_spread":0.2692451512740819,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}