{"id":"W2920846975","doi":"10.1093/jcag/gwz006.219","title":"A220 SCREENING AND MANAGEMENT OF LYNCH SYNDROME IN CLINICAL PRACTICE","year":2019,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Connective tissue disorders research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Medicine; Colonoscopy; Lynch syndrome; Colorectal cancer; Microsatellite instability; Logistic regression; Internal medicine; Family medicine; Univariate analysis; Family history; Clinical Practice; Multivariate analysis; Cancer; DNA mismatch repair","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002073555,0.0001027092,0.0002220784,0.001101115,0.0008957275,0.001364314,0.000604737,0.0006205927,0.00389803],"category_scores_gemma":[0.01969313,0.0001929525,0.0001904015,0.00181952,0.000535802,0.0008408882,0.0009911021,0.0005246616,0.000437849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002102556,"about_ca_system_score_gemma":0.00697528,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.05114119,"about_ca_topic_score_gemma":0.06321266,"domain_scores_codex":[0.99704,0.001204125,0.0003235259,0.0002917986,0.0008384766,0.0003019921],"domain_scores_gemma":[0.9886732,0.002155365,0.004787453,0.0002174588,0.002037257,0.00212932],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006707756,0.0001776529,0.9655781,0.0001327302,0.00001616714,0.0002725355,0.0009730764,0.00006094442,0.000123149,0.0001819176,0.003621999,0.02879458],"study_design_scores_gemma":[0.00002098115,0.0001711882,0.9917607,0.0002638034,0.00001584181,0.0005680813,0.003127251,0.0004683166,0.00004291484,0.0001864605,0.003364258,0.00001027358],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9690226,0.004634716,0.0003724185,0.01201013,0.0000832828,0.0003091986,0.0008449857,0.00002844314,0.01269409],"genre_scores_gemma":[0.9941136,0.002557527,0.001346802,0.0008925575,0.00006913482,0.0001291185,0.0003060076,0.000003598132,0.000581615],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.05114119,"threshold_uncertainty_score":0.1016871,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01241210717253061,"score_gpt":0.30289077988241,"score_spread":0.2904786727098794,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}