{"id":"W2920869063","doi":"10.1093/jcag/gwz006.039","title":"A40 IBD PATIENTS RECEIVING INFLIXIMAB IN COMBINATION WITH AN IMMUNOMODULATOR ARE LESS LIKELY TO DEVELOP SECONDARY LOSS OF RESPONSE","year":2019,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Medicine; Infliximab; Ulcerative colitis; Internal medicine; Adalimumab; Demographics; Cohort; Pancolitis; Disease; Inflammatory bowel disease; Log-rank test; Gastroenterology; Immunology; Survival analysis; Cancer; Colorectal cancer; Demography","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003162502,0.0001253222,0.0003123682,0.0004385616,0.000377997,0.0005997776,0.0001283274,0.0003522893,0.007825716],"category_scores_gemma":[0.001908907,0.0001306884,0.0002529197,0.0005055185,0.0001932202,0.0003418708,0.0002110647,0.0004446153,0.00118268],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002064955,"about_ca_system_score_gemma":0.0002844027,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001751205,"about_ca_topic_score_gemma":0.00217487,"domain_scores_codex":[0.9997005,0.00007136896,0.00002653104,0.00004516827,0.00008622609,0.00007005139],"domain_scores_gemma":[0.9985878,0.000205424,0.0007541162,0.00005820684,0.0001185283,0.0002758293],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003249317,0.000121374,0.9859276,0.00003022468,0.00003338937,0.0004281648,0.0001255098,0.00004355049,0.001246639,0.00005021692,0.0005309048,0.01113741],"study_design_scores_gemma":[0.00001836833,0.0003379848,0.9959301,0.00001573514,0.00001387384,0.001628753,0.00018262,0.0001120525,0.0001213374,0.00004482394,0.001590049,0.000004264958],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977474,0.0005016579,0.00006031258,0.00009355552,0.000009535849,0.000007041669,0.0001203598,0.000005883343,0.00145431],"genre_scores_gemma":[0.9989722,0.0001876763,0.00005554901,0.0001047179,0.00001636268,0.000004583397,0.0001643929,0.000002645446,0.0004919812],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007825716,"threshold_uncertainty_score":0.02617961,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004392864407310945,"score_gpt":0.1914433960532175,"score_spread":0.1870505316459065,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}