{"id":"W2920970793","doi":"10.1093/jcag/gwz006.041","title":"A42 SPECIES SPECIFIC BACTERIAL LIPOPOLYSACCHARIDES INDIVIDUALLY MODULATE INTESTINAL EPITHELIAL PERMEABILITY AND INFLAMMATION THROUGH TOLL-LIKE RECEPTOR 4","year":2019,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Lipopolysaccharide; TLR4; CD14; Cytokine; Inflammation; Inflammatory bowel disease; Intestinal permeability; Toll-like receptor; Microbiology; Molecular biology; Stimulation; Biology; Chemistry; Receptor; Immunology; Medicine; Pathology; Flow cytometry; Biochemistry; Innate immune system; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000123738,0.0003004399,0.0002581009,0.0002481622,0.0001171617,0.0002443528,0.0000789031,0.0002658118,0.002215665],"category_scores_gemma":[0.0001448229,0.0001473234,0.0003086472,0.0001465718,0.0001527848,0.0002287661,0.0002768164,0.0004735024,0.0004089916],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009603462,"about_ca_system_score_gemma":0.0001076358,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001204423,"about_ca_topic_score_gemma":0.0001820296,"domain_scores_codex":[0.9998159,0.00005640238,0.00001662504,0.00002177176,0.00003205437,0.00005736986],"domain_scores_gemma":[0.9999117,0.00001020553,0.00002488241,0.000006779338,0.00001226407,0.00003414593],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009986416,0.0001227228,0.001192569,0.00006552441,0.00001174399,0.00005120655,0.0000182872,0.00002583896,0.9956477,0.00002239539,0.00005859499,0.001784711],"study_design_scores_gemma":[0.0002340061,0.009519847,0.1452966,0.00007223521,0.0001316867,0.00117255,0.0005590316,0.001792188,0.8353055,0.0003621742,0.005527752,0.00002652564],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970901,0.001706403,0.0003530708,0.00007620096,0.00002504728,0.00001785911,0.0001379615,0.00001639404,0.0005769767],"genre_scores_gemma":[0.9969886,0.0009837896,0.0006101961,0.00008225237,0.00001602233,0.00004145568,0.0002909416,0.000005809835,0.0009810164],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002215665,"threshold_uncertainty_score":0.007412076,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00668665955204818,"score_gpt":0.1979305969456841,"score_spread":0.1912439373936359,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}