{"id":"W2920987196","doi":"10.1111/imr.12731","title":"Germinal center B cell initiation, GC maturation, and the coevolution of its stromal cell niches","year":2019,"lang":"en","type":"review","venue":"Immunological Reviews","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Institutes of Health; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Multiple Sclerosis Society; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Multiple Sclerosis Society of Canada","keywords":"Biology; Coevolution; Context (archaeology); Niche; Germinal center; Stromal cell; Ecological niche; Evolutionary biology; Genetics; B cell; Ecology; Cancer research","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003448941,0.0006555007,0.000836025,0.00138421,0.0002182394,0.0008996435,0.000585701,0.0008795224,0.001856091],"category_scores_gemma":[0.0003183954,0.000213242,0.000206307,0.001307133,0.0004798641,0.001024604,0.0005759877,0.001246506,0.001921454],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007062753,"about_ca_system_score_gemma":0.0007459199,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000772416,"about_ca_topic_score_gemma":0.0008227783,"domain_scores_codex":[0.9998889,0.00001627253,0.00001187354,0.00002601372,0.0000388583,0.00001797003],"domain_scores_gemma":[0.999879,0.000040338,0.00002149574,0.00000370398,0.00003530501,0.00002025755],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001083532,0.00004705191,0.0002305733,0.01243133,0.00003696138,0.0003998154,0.0001124097,0.0004255782,0.01068702,0.008634502,0.02388902,0.9429974],"study_design_scores_gemma":[0.000007058958,0.00008510673,0.001310673,0.001762798,0.00002978253,0.001684958,0.00008480097,0.00007347512,0.001673208,0.002656347,0.9906169,0.00001491392],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002517772,0.9979388,0.000158441,0.0002082753,0.000285747,0.000002659292,0.0000102491,0.000008169874,0.001135913],"genre_scores_gemma":[0.001217496,0.9973544,0.0001732774,0.0001273371,0.0002587036,0.000004146248,0.00002031629,0.000001824958,0.0008425764],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001856091,"threshold_uncertainty_score":0.006209254,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05585979042705542,"score_gpt":0.2969113157326188,"score_spread":0.2410515253055634,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}