{"id":"W2921059178","doi":"10.1161/atvb.38.suppl_1.257","title":"Abstract 257: Apabetalone (RVX-208) Reduces Pathologic Cell-Cell Adhesion and Expression of Key Vascular Inflammation Markers in Monocytes, Endothelial Cells and Mouse Aorta","year":2018,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Resverlogix (Canada)","funders":"","keywords":"Inflammation; Cell adhesion molecule; Medicine; Endothelium; Tumor necrosis factor alpha; Proinflammatory cytokine; Endothelial activation; Monocyte; Immunology; Endothelial stem cell; Cell adhesion; Umbilical vein; Internal medicine; Endocrinology; Biology; Cell; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008196464,0.0004410706,0.0003572636,0.0002466078,0.0001291578,0.0002568857,0.0001884552,0.000345582,0.003794261],"category_scores_gemma":[0.00008218003,0.000150448,0.000272198,0.0001429856,0.0001671372,0.0001619113,0.0001305702,0.0009130704,0.000616355],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001446438,"about_ca_system_score_gemma":0.0002001375,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006094286,"about_ca_topic_score_gemma":0.0007820834,"domain_scores_codex":[0.9999198,0.00001204245,0.000009457162,0.00001476229,0.00001731145,0.00002666164],"domain_scores_gemma":[0.999925,0.000007200646,0.0000227484,0.000007149013,0.000007680239,0.00003018194],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001262954,0.000251516,0.0001576851,0.00009343576,0.00001154053,0.00005755861,0.000009321836,0.00004237926,0.9946737,0.00004891602,0.0001644014,0.003226666],"study_design_scores_gemma":[0.0003470566,0.007115057,0.007203686,0.00002082811,0.00006466432,0.0003058276,0.00003281879,0.0004225417,0.981452,0.00005827256,0.002969194,0.00000796207],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994118,0.002281233,0.0008658352,0.0001761952,0.00009679324,0.00003960498,0.0008249232,0.0001438096,0.001453598],"genre_scores_gemma":[0.9881988,0.002189635,0.001072823,0.0001690659,0.00003543121,0.00006850445,0.001292595,0.00002129374,0.006951732],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003794261,"threshold_uncertainty_score":0.01269305,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0206513955016881,"score_gpt":0.248849495098425,"score_spread":0.228198099596737,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}