{"id":"W2921106016","doi":"10.1007/s00401-019-01987-0","title":"cIMPACT-NOW update 4: diffuse gliomas characterized by MYB, MYBL1, or FGFR1 alterations or BRAFV600E mutation","year":2019,"lang":"en","type":"letter","venue":"Acta Neuropathologica","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":252,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Mutation; Cancer research; MYB; Glioma; Medicine; Pathology; Biology; Genetics; Gene; Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006176378,0.0008314834,0.0009272824,0.0009796754,0.001139065,0.001588642,0.000830445,0.01341604,0.005534414],"category_scores_gemma":[0.005940309,0.0004104019,0.0009288383,0.0005443349,0.0008853484,0.001370853,0.0007144715,0.007639682,0.00511701],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002502417,"about_ca_system_score_gemma":0.001397383,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00373769,"about_ca_topic_score_gemma":0.006370877,"domain_scores_codex":[0.9993327,0.0001221436,0.0001226196,0.00006799976,0.0001722577,0.0001823074],"domain_scores_gemma":[0.9985725,0.0004846581,0.0001443129,0.00006155042,0.0003267087,0.0004102635],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002194191,0.0001024116,0.004846444,0.0002462365,0.00004548922,0.1245576,0.0001104036,0.0003547439,0.001029373,0.002659941,0.8282676,0.03756035],"study_design_scores_gemma":[0.0004092415,0.0001946764,0.008896711,0.001060826,0.000183499,0.2718877,0.0002888488,0.001904276,0.001224075,0.009267461,0.7045981,0.00008450968],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"editorial","genre_scores_codex":[0.01368504,0.01354776,0.001495584,0.8437354,0.06447478,0.0001964971,0.001195995,0.0003635381,0.0613054],"genre_scores_gemma":[0.1192997,0.02267921,0.003907013,0.5655891,0.229809,0.000280421,0.001753491,0.0002593658,0.05642258],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.01341604,"threshold_uncertainty_score":0.01851445,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02948175259798109,"score_gpt":0.2785274313116085,"score_spread":0.2490456787136274,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}