{"id":"W2921163585","doi":"10.3390/cancers11030351","title":"Development of DNA Aptamers to Native EpCAM for Isolation of Lung Circulating Tumor Cells from Human Blood","year":2019,"lang":"en","type":"article","venue":"Cancers","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Aptamer; Epithelial cell adhesion molecule; Lung cancer; Circulating tumor cell; Antibody; Molecular biology; Cancer research; Cancer cell; Biology; Chemistry; Cancer; Pathology; Medicine; Immunology; Metastasis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002923225,0.0003244049,0.0002950145,0.000303152,0.00009965634,0.000254776,0.0002856794,0.0004188089,0.000759765],"category_scores_gemma":[0.000579825,0.0001890487,0.0001489938,0.0001675755,0.0001285921,0.0001352332,0.0001817772,0.0005138002,0.0005052747],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002372715,"about_ca_system_score_gemma":0.0001920062,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000353445,"about_ca_topic_score_gemma":0.0005315694,"domain_scores_codex":[0.9997459,0.00004031049,0.00001885808,0.00009650231,0.00006775891,0.00003064356],"domain_scores_gemma":[0.9997936,0.00007327226,0.00002711777,0.00001612646,0.00006016306,0.00002969875],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000230646,0.00001348165,0.0001241262,0.00002459946,0.000002749975,0.0000285622,0.00001457632,0.00008506539,0.9953229,0.00005495593,0.00003644809,0.004269633],"study_design_scores_gemma":[0.00001848453,0.0001277649,0.0008664026,0.000003678443,0.000007839603,0.0002627534,0.000006546624,0.002765388,0.9941526,0.00005785163,0.001726388,0.000004309235],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7619646,0.004110698,0.229213,0.0003737422,0.00015364,0.0004582345,0.0005845572,0.0006697365,0.002471843],"genre_scores_gemma":[0.8587469,0.001032659,0.1345257,0.0002890865,0.00004872284,0.0003466181,0.0007067716,0.00005685666,0.004246654],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000759765,"threshold_uncertainty_score":0.002541602,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009945436347085106,"score_gpt":0.2785023235595411,"score_spread":0.268556887212456,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}