{"id":"W2921163585","doi":"10.3390/cancers11030351","title":"Development of DNA Aptamers to Native EpCAM for Isolation of Lung Circulating Tumor Cells from Human Blood","year":2019,"lang":"en","type":"article","venue":"Cancers","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Aptamer; Epithelial cell adhesion molecule; Lung cancer; Circulating tumor cell; Antibody; Molecular biology; Cancer research; Cancer cell; Biology; Chemistry; Cancer; Pathology; Medicine; Immunology; Metastasis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008214115,0.00008883668,0.0001619863,0.00004130276,0.00003350128,0.000002927522,0.00007557984,0.00004948707,0.000002776204],"category_scores_gemma":[0.00001899592,0.00008675288,0.00006960209,0.00007617941,0.00002845737,0.000002398614,0.00003052057,0.0000248593,2.466599e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007509493,"about_ca_system_score_gemma":0.0001088954,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003060892,"about_ca_topic_score_gemma":0.00003461533,"domain_scores_codex":[0.9993464,0.00001089423,0.0002350633,0.0002226363,0.00007782778,0.000107188],"domain_scores_gemma":[0.9994932,0.00001040242,0.0001993649,0.0001488609,0.0001188396,0.00002936611],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002871933,0.000007708509,0.0006328088,0.00002595004,0.0001035146,8.492427e-8,0.0001937238,0.0001555068,0.9979811,0.000009233663,0.00005031022,0.0008112972],"study_design_scores_gemma":[0.000238312,0.0001021299,0.0003698856,0.00005347199,0.00003938077,1.391082e-7,0.0002401119,0.0002753737,0.9979017,0.00001724754,0.0006489989,0.0001132368],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933546,0.00003764611,0.006079123,0.000005187632,0.0000426922,0.0002490291,0.00004861101,0.000007438648,0.0001756981],"genre_scores_gemma":[0.9463252,0.000003185896,0.05341187,0.00005030256,0.00003508464,0.00001061907,0.0001009877,0.00001059847,0.00005214119],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04733275,"threshold_uncertainty_score":0.353768,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009945436347085106,"score_gpt":0.2785023235595411,"score_spread":0.268556887212456,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}