{"id":"W2921227502","doi":"10.1093/infdis/jiz100","title":"Impact of Treatment Interruption on HIV Reservoirs and Lymphocyte Subsets in Individuals Who Initiated Antiretroviral Therapy During the Early Phase of Infection","year":2019,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Maple Leaf Medical Clinic","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Institutes of Health","keywords":"Antiretroviral therapy; Human immunodeficiency virus (HIV); Immunology; Medicine; Lymphocyte subsets; Antiretroviral treatment; Lymphocyte; Virology; Viral load; Intensive care medicine; Immune system; CD8","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001022641,0.0001573348,0.0004921005,0.0001533577,0.0002813092,0.0004732321,0.0001860701,0.0003373824,0.001186289],"category_scores_gemma":[0.004266204,0.00006783052,0.0001993631,0.0001341377,0.000180834,0.0002680902,0.0002477643,0.0007096113,0.000104837],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002769898,"about_ca_system_score_gemma":0.0003485974,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005608067,"about_ca_topic_score_gemma":0.0008520509,"domain_scores_codex":[0.999145,0.0004686005,0.00004257789,0.00004864792,0.00009982171,0.0001953149],"domain_scores_gemma":[0.9973372,0.001441873,0.0004592206,0.0001898477,0.0001695686,0.0004022965],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0770172,0.005917021,0.463107,0.0004269437,0.0005197673,0.001717182,0.001715973,0.001168522,0.06688571,0.0009100664,0.002515718,0.3780989],"study_design_scores_gemma":[0.0006952015,0.03308173,0.9405364,0.0001223272,0.0005313475,0.00183211,0.0006343013,0.001213045,0.01094034,0.0006821309,0.009703028,0.0000279723],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950426,0.00209765,0.0001363692,0.0002775626,0.0000300728,0.00002682616,0.0000633475,0.00001300135,0.002312478],"genre_scores_gemma":[0.9992425,0.0001986812,0.00007533777,0.0001680103,0.00002146893,0.00001511428,0.00004369386,0.00000248963,0.0002327056],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001186289,"threshold_uncertainty_score":0.005408287,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02761816909082019,"score_gpt":0.3322370686695044,"score_spread":0.3046188995786842,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}