{"id":"W2921271190","doi":"10.1161/atvb.38.suppl_1.456","title":"Abstract 456: LncRNA <i>CHROME</i> is Increased in Cardiovascular Disease and Regulates Inflammatory Gene Expression","year":2018,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Berger (Canada)","funders":"","keywords":"Biology; Gene expression; Chromatin; Epigenetics; Gene knockdown; Transcriptome; Gene; Chromatin immunoprecipitation; RNA; Regulation of gene expression; DNA methylation; Transcription factor; Histone; Molecular biology; Cell biology; Promoter; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001419172,0.0004555062,0.0003149096,0.0002928818,0.0003725056,0.0005054628,0.0001949897,0.0004310616,0.008597142],"category_scores_gemma":[0.0001580219,0.0001366273,0.0004428532,0.0003369697,0.0002560521,0.0002065692,0.0002868951,0.0006173507,0.001879852],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003533115,"about_ca_system_score_gemma":0.0002244046,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009852317,"about_ca_topic_score_gemma":0.00124824,"domain_scores_codex":[0.9997664,0.00001610308,0.000009748373,0.0001150199,0.00006495089,0.00002769718],"domain_scores_gemma":[0.9998717,0.00001795689,0.00004267966,0.00001099793,0.00002041194,0.00003619879],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003221483,0.00001971893,0.002376355,0.000190854,0.00003632335,0.0002041658,0.00002665689,0.00004317204,0.9909965,0.0002076982,0.001282434,0.004294033],"study_design_scores_gemma":[0.00010254,0.000625425,0.2080379,0.00009570746,0.0002607828,0.004266619,0.0001089944,0.00153146,0.7209018,0.0005911717,0.06341659,0.00006096092],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8971048,0.0179754,0.0213249,0.002406653,0.001341065,0.0001361905,0.03555746,0.002382311,0.02177126],"genre_scores_gemma":[0.929565,0.003946578,0.009777208,0.002359838,0.0004803628,0.0001179913,0.01995668,0.0003354548,0.03346086],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008597142,"threshold_uncertainty_score":0.02876025,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01620272668584621,"score_gpt":0.2588903920602477,"score_spread":0.2426876653744015,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}