{"id":"W2921338596","doi":"10.3389/fendo.2019.00162","title":"Asymmetric Recruitment of β-Arrestin1/2 by the Angiotensin II Type I and Prostaglandin F2α Receptor Dimer","year":2019,"lang":"en","type":"article","venue":"Frontiers in Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; McGill University; University of Missouri","keywords":"Receptor; Angiotensin II; G protein-coupled receptor; Cell biology; HEK 293 cells; Chemistry; Dimer; Internal medicine; Prostaglandin; Biology; Endocrinology; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002185638,0.0002396448,0.0004863107,0.0001528252,0.0001690237,0.0005512294,0.0002525082,0.0004274595,0.0009722554],"category_scores_gemma":[0.0002331966,0.0002437722,0.0003755071,0.0001268886,0.0001920216,0.000313757,0.0002593983,0.0009141114,0.0006841616],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004113835,"about_ca_system_score_gemma":0.0001741829,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005026356,"about_ca_topic_score_gemma":0.0007184613,"domain_scores_codex":[0.9996284,0.0000362002,0.00002202591,0.0001118397,0.0001123024,0.00008920833],"domain_scores_gemma":[0.9998888,0.00002082221,0.00003084799,0.00001421405,0.00001766917,0.00002760511],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004928964,0.000009256622,0.0001126555,0.00003085291,0.000004651447,0.00004332722,0.00001698669,0.0000673786,0.9988301,0.0001521787,0.00009841306,0.0005848734],"study_design_scores_gemma":[0.00002163618,0.0001133819,0.006818222,0.00001247563,0.00001123096,0.0003308703,0.00006672399,0.006282553,0.9814146,0.0001106152,0.004800814,0.0000168531],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841686,0.002013844,0.009924036,0.0002803445,0.0001003924,0.00005781871,0.0004754518,0.0001685811,0.002810917],"genre_scores_gemma":[0.990159,0.0009881514,0.003825575,0.0002134395,0.00002167999,0.00008416137,0.0004239572,0.00004816999,0.004235822],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009722554,"threshold_uncertainty_score":0.003252447,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01293820742112528,"score_gpt":0.2395803269090843,"score_spread":0.226642119487959,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}