{"id":"W2921464684","doi":"10.1002/btpr.2800","title":"Expansion of retinal stem cells and their progeny using cell microcarriers in a bioreactor","year":2019,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Foundation Medicine; Ontario Institute for Regenerative Medicine; Krembil Foundation","keywords":"Retinitis pigmentosa; Microcarrier; Transplantation; Bioreactor; Stem cell; Biology; Retinal; Hypoxia (environmental); Cell biology; Retina; Cell culture; Chemistry; Genetics; Medicine; Surgery; Botany; Neuroscience","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002879389,0.0003137462,0.0001793425,0.000227735,0.0001424983,0.0002886513,0.0002067092,0.0002219298,0.0006062366],"category_scores_gemma":[0.0001470451,0.00009259332,0.0002120929,0.0001396619,0.0001472717,0.0001573255,0.0001816062,0.0003397282,0.000348529],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000223462,"about_ca_system_score_gemma":0.0001482665,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00106946,"about_ca_topic_score_gemma":0.001263256,"domain_scores_codex":[0.9998696,0.00001855229,0.00001690137,0.0000304704,0.00004873662,0.00001566496],"domain_scores_gemma":[0.9998472,0.0000434927,0.00003641638,0.00001837108,0.00003112495,0.00002334345],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001900962,0.00001026542,0.0001650359,0.00001468499,0.000002348222,0.00002255255,0.00001981644,0.0001600993,0.9985744,0.0000432776,0.00002570209,0.0009427269],"study_design_scores_gemma":[0.000002362456,0.00009594699,0.0007996898,0.00000369828,0.000008802219,0.00003932297,0.00001124827,0.001142905,0.9964948,0.00001446533,0.001383634,0.000003065292],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9678066,0.00115883,0.02868912,0.00009989413,0.00006727014,0.00009675185,0.0003300434,0.0002659528,0.001485493],"genre_scores_gemma":[0.9615663,0.0008133368,0.03307694,0.00006293692,0.00002312678,0.0001315138,0.0004420922,0.0000555061,0.003828185],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00106946,"threshold_uncertainty_score":0.002126515,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006718099245892853,"score_gpt":0.2122048735718416,"score_spread":0.2054867743259488,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}