{"id":"W2921464684","doi":"10.1002/btpr.2800","title":"Expansion of retinal stem cells and their progeny using cell microcarriers in a bioreactor","year":2019,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Foundation Medicine; Ontario Institute for Regenerative Medicine; Krembil Foundation","keywords":"Retinitis pigmentosa; Microcarrier; Transplantation; Bioreactor; Stem cell; Biology; Retinal; Hypoxia (environmental); Cell biology; Retina; Cell culture; Chemistry; Genetics; Medicine; Surgery; Botany; Neuroscience","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001101766,0.0001469389,0.0001726577,0.0001179533,0.00002094198,0.000006853712,0.0001564187,0.0004059287,0.000002834149],"category_scores_gemma":[0.000003332671,0.0001236796,0.00003706751,0.0001400082,0.0002388406,0.000003429972,0.0001551327,0.00009406659,0.000002110911],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009761724,"about_ca_system_score_gemma":0.00006719297,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006760231,"about_ca_topic_score_gemma":0.000002927517,"domain_scores_codex":[0.9991813,0.00002715834,0.0001887102,0.000328851,0.00005224657,0.0002217071],"domain_scores_gemma":[0.999605,0.000004158814,0.0001098859,0.0002224242,0.00002843599,0.0000300753],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001040489,0.00003392108,0.08634954,0.00006533061,0.00001026914,0.000001800222,0.00006679215,7.041093e-7,0.9091315,0.00002010616,0.00001185678,0.004204127],"study_design_scores_gemma":[0.0005359945,0.0002547612,0.001710259,0.00003933744,0.000004241146,0.000009699414,0.0005645987,0.00005333265,0.9948927,0.00001530407,0.001769812,0.0001499753],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968672,0.002516919,0.00004600109,0.00006541362,0.0000646449,0.0003616982,0.000007047504,0.00001531002,0.00005570834],"genre_scores_gemma":[0.9981086,0.0002276916,0.001561479,0.00001688571,0.00000709398,0.000009116544,0.000009661894,0.00001486578,0.00004460146],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08576118,"threshold_uncertainty_score":0.5043507,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006718099245892853,"score_gpt":0.2122048735718416,"score_spread":0.2054867743259488,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}