{"id":"W2921545642","doi":"10.2337/db18-0837","title":"Diabetes-Induced DUSP4 Reduction Promotes Podocyte Dysfunction and Progression of Diabetic Nephropathy","year":2019,"lang":"en","type":"article","venue":"Diabetes","topic":"Biomedical Research and Pathophysiology","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Institute of Nutrition, Metabolism and Diabetes; Canadian Institutes of Health Research","keywords":"Podocyte; Diabetic nephropathy; p38 mitogen-activated protein kinases; Diabetes mellitus; Medicine; Internal medicine; Endocrinology; Renal function; Protein kinase A; Kinase; Downregulation and upregulation; Kidney; Cell biology; Biology; Proteinuria; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001828594,0.0003455491,0.000379806,0.000268263,0.0001501379,0.000200214,0.0001581405,0.0002287737,0.0008859712],"category_scores_gemma":[0.00009378158,0.000136183,0.0003921048,0.0001780758,0.0001419524,0.0002084947,0.0002402591,0.0009435666,0.0001512359],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001803839,"about_ca_system_score_gemma":0.0002187819,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000519196,"about_ca_topic_score_gemma":0.0005661937,"domain_scores_codex":[0.9998858,0.00001856473,0.00001351741,0.00002038494,0.00002672172,0.00003502802],"domain_scores_gemma":[0.9999057,0.000005038532,0.00002374669,0.000007579142,0.00001507718,0.00004295113],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004825901,0.0001013499,0.000610514,0.00006604539,0.0000173686,0.00008216315,0.00001686968,0.00003644184,0.9961275,0.00005958566,0.00005691471,0.002342637],"study_design_scores_gemma":[0.00008637679,0.002468882,0.03320402,0.00002304147,0.0000903179,0.0006211089,0.00008150435,0.001552911,0.9587767,0.0001798457,0.002902749,0.00001255474],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936463,0.002713011,0.002592178,0.0001054066,0.00004125119,0.00002475882,0.0001414574,0.00009334921,0.0006423279],"genre_scores_gemma":[0.9959366,0.001372597,0.001170045,0.00008719181,0.00001092079,0.00003142685,0.0002404767,0.00001040518,0.001140265],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008859712,"threshold_uncertainty_score":0.002963841,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01392883962207672,"score_gpt":0.2780578481639394,"score_spread":0.2641290085418627,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}