{"id":"W2921549065","doi":"10.1093/jcag/gwz006.017","title":"A18 STRESS TRIGGERS LOSS OF TOLERANCE TO FOOD ANTIGEN CAUSING HISTAMINE MEDIATED NEURON HYPEREXCITABILITY IN A PRECLINICAL MODEL OF IBS.","year":2019,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Gastrointestinal motility and disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Histamine; Ovalbumin; Antigen; Sensitization; Immune system; Immunology; Mast cell; Medicine; Endocrinology; Chemistry; Internal medicine; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003616938,0.001329758,0.0005977415,0.000754561,0.0003749727,0.0003318909,0.0005469728,0.001074322,0.003541765],"category_scores_gemma":[0.0001430344,0.0005538632,0.0009125529,0.0003264937,0.0006331659,0.0005821022,0.0003529065,0.002722774,0.0007585468],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005333681,"about_ca_system_score_gemma":0.000538271,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008064774,"about_ca_topic_score_gemma":0.001850339,"domain_scores_codex":[0.9996868,0.00003722632,0.00002612882,0.00005760845,0.0000524596,0.000139862],"domain_scores_gemma":[0.999624,0.00002421435,0.000106248,0.00004080013,0.00002276768,0.0001819],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004235402,0.00272644,0.0006838643,0.0001518745,0.00003886165,0.0003764563,0.0000892345,0.0001606708,0.9891303,0.0001656386,0.0003603916,0.001880786],"study_design_scores_gemma":[0.001646344,0.151275,0.0358073,0.000134784,0.000177781,0.001539617,0.0004478951,0.002100526,0.8020782,0.0004925169,0.004244525,0.0000555994],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957597,0.0007975387,0.0006531689,0.0003302971,0.0002429591,0.0001799925,0.0008534359,0.00009185376,0.001091184],"genre_scores_gemma":[0.9861552,0.002106459,0.001886215,0.0003155091,0.0001000304,0.0006220969,0.001669372,0.00003574459,0.007109409],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003541765,"threshold_uncertainty_score":0.01184839,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02469225322671589,"score_gpt":0.2594269245232734,"score_spread":0.2347346712965575,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}