{"id":"W2921604675","doi":"10.1200/jco.2019.37.7_suppl.422","title":"Randomized phase I trial of pembrolizumab with neo-adjuvant versus concomitant stereotactic body radiotherapy in metastatic urothelial carcinoma: Clinical and translational results.","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Medicine; Pembrolizumab; Adverse effect; Concomitant; Common Terminology Criteria for Adverse Events; Internal medicine; Randomized controlled trial; Oncology; Response Evaluation Criteria in Solid Tumors; Clinical trial; Surgery; Phases of clinical research; Cancer; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002694051,0.002345538,0.003265565,0.0006281141,0.0006373786,0.001642516,0.001373841,0.002780189,0.008366853],"category_scores_gemma":[0.002267901,0.001098635,0.002093238,0.0006326049,0.0015669,0.001433683,0.0005893048,0.004451561,0.001659603],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001570707,"about_ca_system_score_gemma":0.002802527,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001140039,"about_ca_topic_score_gemma":0.003309218,"domain_scores_codex":[0.9991334,0.0004520018,0.00004137579,0.0001643147,0.00006090188,0.0001481625],"domain_scores_gemma":[0.9985778,0.0002456165,0.0003653837,0.0001275143,0.00009624415,0.0005873978],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9728343,0.01174886,0.0003025935,0.0004201179,0.000673956,0.00004221994,0.00005050059,0.0003443081,0.003362607,0.0001199115,0.001112598,0.008988171],"study_design_scores_gemma":[0.9370663,0.06090466,0.0005412872,0.00001751514,0.0002166672,0.00002465996,0.00001202384,0.0002314872,0.0002635471,0.0001383629,0.0005747486,0.000008729248],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9560262,0.007230837,0.001606628,0.002584396,0.001649704,0.02211194,0.003729243,0.0003102059,0.004750967],"genre_scores_gemma":[0.9543222,0.003949599,0.004210135,0.002969862,0.0008714084,0.02280174,0.003761181,0.00006737008,0.00704658],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008366853,"threshold_uncertainty_score":0.02798992,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1227056959716152,"score_gpt":0.4737296795899862,"score_spread":0.3510239836183709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}