{"id":"W2921795623","doi":"10.1161/res.119.suppl_1.230","title":"Abstract 230: Humoral Immune Response Against <i>Trypanosoma</i> c <i>ruzi</i> Infection Using Plasmid DNA Immunotherapy in the Experimental Canine Model of Chagas Disease","year":2016,"lang":"en","type":"article","venue":"Circulation Research","topic":"Animal Genetics and Reproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Trypanosoma cruzi; Plasmid; Chagas disease; Immunotherapy; Immunology; Immune system; Antibody; Virology; Biology; Antigen; Vector (molecular biology); Trypanosomiasis; Medicine; Recombinant DNA; Parasite hosting; DNA; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007892821,0.0001194671,0.0001091898,0.0001300334,0.000163116,0.00002735839,0.0001601886,0.0001009255,0.00001270033],"category_scores_gemma":[0.0001135002,0.00008367385,0.00008630199,0.000205817,0.0002035285,0.00001463303,0.00006427549,0.0001162151,0.000003769704],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007075255,"about_ca_system_score_gemma":0.0002085098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001100937,"about_ca_topic_score_gemma":0.00001354723,"domain_scores_codex":[0.9984319,0.0002735171,0.000296021,0.0003498332,0.000385835,0.0002629039],"domain_scores_gemma":[0.9991931,0.00003278648,0.0000933048,0.0004530462,0.0001743307,0.00005342278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001279638,0.0001704165,0.00373651,0.00001072356,0.00001354355,0.000002014519,0.0001490046,0.01627134,0.977792,0.0000541518,0.00004027244,0.0004804095],"study_design_scores_gemma":[0.00105898,0.0001866101,0.3463995,0.00005007917,0.000003806399,0.000004978854,0.0001264308,0.007103965,0.6444594,0.0001011159,0.0003350846,0.0001699833],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978042,0.000729882,0.0005699809,0.0003067712,0.00006855935,0.0003628171,0.00001723412,0.000006239642,0.0001343465],"genre_scores_gemma":[0.9993685,0.0002427894,0.00004392965,0.00004571725,0.0001360277,0.0000252262,0.0000319769,0.00002398542,0.00008187761],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.342663,"threshold_uncertainty_score":0.3412121,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07449049260517594,"score_gpt":0.3553382214400956,"score_spread":0.2808477288349197,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}