{"id":"W2921795623","doi":"10.1161/res.119.suppl_1.230","title":"Abstract 230: Humoral Immune Response Against <i>Trypanosoma</i> c <i>ruzi</i> Infection Using Plasmid DNA Immunotherapy in the Experimental Canine Model of Chagas Disease","year":2016,"lang":"en","type":"article","venue":"Circulation Research","topic":"Animal Genetics and Reproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Trypanosoma cruzi; Plasmid; Chagas disease; Immunotherapy; Immunology; Immune system; Antibody; Virology; Biology; Antigen; Vector (molecular biology); Trypanosomiasis; Medicine; Recombinant DNA; Parasite hosting; DNA; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003006163,0.0006639355,0.0006064235,0.0005235184,0.0002208457,0.0003415377,0.0002410413,0.0006851465,0.001916375],"category_scores_gemma":[0.0001651834,0.0002210993,0.0004550107,0.0001687057,0.0005154663,0.000359884,0.0001912821,0.001748988,0.0005165019],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004199486,"about_ca_system_score_gemma":0.0002886114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005481238,"about_ca_topic_score_gemma":0.0005383968,"domain_scores_codex":[0.9996588,0.00005510603,0.0000222505,0.00006716852,0.00008525617,0.0001113612],"domain_scores_gemma":[0.9997553,0.00004049222,0.00004544461,0.0000212185,0.0000307238,0.00010679],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001975103,0.001670103,0.0003958019,0.00009497091,0.00001703014,0.00009607537,0.00004675218,0.0001252284,0.9931535,0.0001083822,0.0002250433,0.002091956],"study_design_scores_gemma":[0.0007616089,0.04633905,0.01134923,0.00003581174,0.00009507159,0.0007840766,0.00009601427,0.002219688,0.9343695,0.0001503053,0.00377546,0.00002404268],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965001,0.0007662083,0.0007507603,0.0001845428,0.00009430902,0.0001096189,0.0002585775,0.00009487853,0.001240857],"genre_scores_gemma":[0.9931837,0.0006395035,0.001425879,0.0002016067,0.00008398804,0.0002023586,0.0009879235,0.00002047522,0.003254733],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001916375,"threshold_uncertainty_score":0.006410897,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07449049260517594,"score_gpt":0.3553382214400956,"score_spread":0.2808477288349197,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}