{"id":"W2921821235","doi":"10.1074/jbc.ra119.007653","title":"NMR– and MD simulation–based structural characterization of the membrane-associating FATC domain of ataxia telangiectasia mutated","year":2019,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"German Academic Exchange Service London; Technische Universität München; Deutsche Forschungsgemeinschaft; Alberta Innovates - Technology Futures","keywords":"Micelle; Chemistry; Membrane; Biophysics; Vesicle; Crystallography; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002716185,0.0004706723,0.0004090959,0.0002546053,0.0006126171,0.0002552652,0.0006133196,0.0005702236,0.001324948],"category_scores_gemma":[0.0003883633,0.0002645366,0.0004399499,0.0002234666,0.0003799344,0.0004279014,0.0002671604,0.0006184484,0.0001911023],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008190614,"about_ca_system_score_gemma":0.0009389109,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005978658,"about_ca_topic_score_gemma":0.005291742,"domain_scores_codex":[0.9999281,0.00001170064,0.000004578088,0.00001512275,0.00002185634,0.0000187137],"domain_scores_gemma":[0.9998362,0.00005430387,0.00002483039,0.0000150061,0.00003533492,0.00003434669],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.001182833,0.001019347,0.009543804,0.0004065982,0.0002723131,0.000813788,0.0003366741,0.6312981,0.3403992,0.003665063,0.00162254,0.009439841],"study_design_scores_gemma":[0.00006246157,0.0002222847,0.003673662,0.00001030573,0.00003271075,0.00003978368,0.00005684046,0.9752561,0.01968135,0.000264744,0.0006760643,0.00002379454],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996163,0.0001657229,0.001945195,0.00008731965,0.00001331676,0.00001786299,0.0002666333,0.00007034823,0.001270527],"genre_scores_gemma":[0.9948013,0.0002047342,0.003839078,0.00003486752,0.000007164118,0.00004909406,0.0007281147,0.00003006247,0.000305637],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005978658,"threshold_uncertainty_score":0.01188767,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008016887081453426,"score_gpt":0.2311473977378162,"score_spread":0.2231305106563627,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}