{"id":"W2921870084","doi":"10.1016/j.stem.2019.02.013","title":"Close Quarters Can Be a Good Fit for Stem Cells to Become T Cells","year":2019,"lang":"en","type":"letter","venue":"Cell stem cell","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Biology; Mesoderm; Stem cell; Induced pluripotent stem cell; Cell biology; Haematopoiesis; Stromal cell; Mesenchymal stem cell; Organoid; Embryonic stem cell; Cell; Immunology; Genetics; Cancer research; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002200538,0.0007504523,0.0008292102,0.0002742682,0.003184277,0.004250236,0.000791234,0.0317218,0.009807372],"category_scores_gemma":[0.01452769,0.0003983786,0.000762828,0.0002819174,0.00418225,0.005528997,0.002227252,0.02374085,0.007608217],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001977144,"about_ca_system_score_gemma":0.001194539,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001065884,"about_ca_topic_score_gemma":0.002596603,"domain_scores_codex":[0.9976604,0.0007733234,0.000139365,0.0002937433,0.000812293,0.0003208219],"domain_scores_gemma":[0.9963085,0.002474367,0.000281978,0.0002193805,0.0003075655,0.0004081262],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001593557,0.00005412589,0.0003728594,0.00008591646,0.0000182783,0.003974954,0.000355151,0.0001009396,0.001240129,0.0263033,0.9418566,0.02547844],"study_design_scores_gemma":[0.0000640349,0.00008909259,0.0001567621,0.00007526959,0.000008372672,0.002627521,0.0006915331,0.0001394061,0.0005474846,0.03536641,0.9602078,0.00002620419],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0008085696,0.005080459,0.000476773,0.9648129,0.01894333,0.000008337722,0.0000180826,0.00004369429,0.009807804],"genre_scores_gemma":[0.02200744,0.003495777,0.0008273863,0.9151982,0.02441604,0.00003958413,0.00002646339,0.00007285552,0.03391616],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.0317218,"threshold_uncertainty_score":0.03280896,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04010783111700474,"score_gpt":0.2876726499778411,"score_spread":0.2475648188608364,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}