{"id":"W2921930987","doi":"10.1101/576934","title":"Germ Granules Functions are Memorized by Transgenerationally Inherited Small RNAs","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institutes of Health; Israel Science Foundation","keywords":"Biology; RNA interference; Genetics; Mutant; Argonaute; Piwi-interacting RNA; Phenotype; Gene silencing; RNA; Germline; Cell biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000123295,0.0005782069,0.0001641632,0.0002397698,0.0001428724,0.0003926365,0.0003767657,0.0003763683,0.001262465],"category_scores_gemma":[0.0001964539,0.0003002056,0.0003047394,0.00006531418,0.0003939459,0.0003336523,0.0005221093,0.001009373,0.0005272268],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003423884,"about_ca_system_score_gemma":0.0002105558,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006241022,"about_ca_topic_score_gemma":0.0009926453,"domain_scores_codex":[0.9998338,0.00001247906,0.00001549726,0.00004115944,0.0000664308,0.00003066754],"domain_scores_gemma":[0.9995646,0.00007076323,0.0001622185,0.00007825763,0.00003108269,0.00009315685],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000118048,0.000002823036,0.00005833709,0.000005600368,0.000001433156,0.00002538521,0.00000347947,0.00001358629,0.9996204,0.00003680453,0.00000623662,0.0002140255],"study_design_scores_gemma":[0.000005496585,0.00005693303,0.003384587,0.000003990017,0.0000110517,0.0001620153,0.00001185484,0.0005182622,0.9949431,0.00003550527,0.0008635945,0.000003736104],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991133,0.0004990994,0.006186133,0.00006454106,0.00003146215,0.00001651677,0.0002871967,0.000317982,0.001464053],"genre_scores_gemma":[0.9922251,0.0002084112,0.002232858,0.00003935038,0.000009197287,0.00002232716,0.0004028583,0.0001169131,0.004742983],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001262465,"threshold_uncertainty_score":0.004223347,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01268401581713479,"score_gpt":0.1998972619316518,"score_spread":0.187213246114517,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}