{"id":"W2922033790","doi":"10.1200/jco.18.01764","title":"Therapy-Related Cardiac Risk in Childhood Cancer Survivors: An Analysis of the Childhood Cancer Survivor Study","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Chemotherapy-induced cardiotoxicity and mitigation","field":"Medicine","cited_by":147,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Cancer Institute","keywords":"Medicine; Radiation therapy; Cancer; Heart failure; Heart disease; Anthracycline; Cumulative incidence; Internal medicine; Disease; Incidence (geometry); Cardiac toxicity; Pediatrics; Cardiology; Chemotherapy; Breast cancer; Cohort","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001080586,0.0003642906,0.0004937323,0.001073049,0.0003036069,0.0004449751,0.000308566,0.0003142015,0.0009306485],"category_scores_gemma":[0.002366805,0.0002902627,0.001112026,0.001467134,0.0002084512,0.0002657766,0.0004718267,0.0005175338,0.0001060788],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003684595,"about_ca_system_score_gemma":0.000394762,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01387081,"about_ca_topic_score_gemma":0.01298229,"domain_scores_codex":[0.9993576,0.000308949,0.00005134968,0.0001067465,0.00009632335,0.00007900142],"domain_scores_gemma":[0.9982263,0.0003398584,0.0008364141,0.0002084353,0.0001238343,0.0002650954],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00009214433,0.000007848006,0.9990201,0.000005114969,0.0001708503,0.00003689214,0.00002633904,0.00006473272,0.00005535463,0.00001079467,0.00006165681,0.0004481861],"study_design_scores_gemma":[0.000008481242,0.00005231162,0.9992371,0.000004513241,0.00008153543,0.00012451,0.00007226842,0.0002479168,0.00003208027,0.000009820995,0.0001265637,0.000002900264],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985068,0.0003900793,0.0001271736,0.00003809668,0.0000040648,0.000007172736,0.0008178366,0.000003089772,0.0001057271],"genre_scores_gemma":[0.9985039,0.0002325666,0.00008974855,0.00001178467,0.000006161364,0.00000942681,0.001058272,0.000002984144,0.00008507602],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01387081,"threshold_uncertainty_score":0.02758014,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0458068344492423,"score_gpt":0.4221855408516204,"score_spread":0.376378706402378,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}