{"id":"W2922062358","doi":"10.1093/cid/ciz177","title":"Immunogenicity and Safety of the Adjuvanted Recombinant Zoster Vaccine in Chronically Immunosuppressed Adults Following Renal Transplant: A Phase 3, Randomized Clinical Trial","year":2019,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":194,"is_retracted":false,"has_abstract":true,"ca_institutions":"Nova Scotia Health Authority; Izaak Walton Killam Health Centre; Dalhousie University; University Health Network; University of Toronto; University of Alberta; St. Michael's Hospital","funders":"","keywords":"Medicine; Immunogenicity; Placebo; Adverse effect; Vaccination; Immunology; Population; Internal medicine; Transplantation; Clinical trial; Immune system; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002207173,0.0003248996,0.002189346,0.0001083393,0.0001191986,0.00002305947,0.000154007,0.0003339392,0.0002738427],"category_scores_gemma":[0.002789584,0.0002003931,0.001945842,0.000315167,0.0002946376,0.0001230619,0.0001093926,0.0006633708,0.00002442103],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007898834,"about_ca_system_score_gemma":0.0003630646,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001933963,"about_ca_topic_score_gemma":0.0001018232,"domain_scores_codex":[0.9942389,0.00175859,0.002754295,0.0006143101,0.0002750667,0.0003588158],"domain_scores_gemma":[0.9942325,0.004130986,0.0005199318,0.0007534251,0.0001085613,0.0002545578],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.5882151,0.00978199,0.3780363,0.00007863688,0.00141374,0.00005573063,0.00005066341,0.000003418,0.00004117102,0.00002262247,0.0000390379,0.02226165],"study_design_scores_gemma":[0.7712643,0.003011018,0.2218022,0.001001108,0.001512077,0.00001828604,0.000008415853,0.0004848488,0.00004716131,0.0001069308,0.0005623323,0.0001813393],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992039,0.001092428,0.0000485347,0.0002035798,0.002155394,0.003969596,0.0000704339,0.00006991062,0.0003511597],"genre_scores_gemma":[0.9974088,0.001857395,0.00001228045,0.0002510658,0.0001488206,0.0001225374,0.00006048318,0.00003365474,0.0001049647],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1830492,"threshold_uncertainty_score":0.8171794,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01905269099969548,"score_gpt":0.3618134567543754,"score_spread":0.3427607657546799,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}