{"id":"W2922062358","doi":"10.1093/cid/ciz177","title":"Immunogenicity and Safety of the Adjuvanted Recombinant Zoster Vaccine in Chronically Immunosuppressed Adults Following Renal Transplant: A Phase 3, Randomized Clinical Trial","year":2019,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":194,"is_retracted":false,"has_abstract":true,"ca_institutions":"Nova Scotia Health Authority; Izaak Walton Killam Health Centre; Dalhousie University; University Health Network; University of Toronto; University of Alberta; St. Michael's Hospital","funders":"","keywords":"Medicine; Immunogenicity; Placebo; Adverse effect; Vaccination; Immunology; Population; Internal medicine; Transplantation; Clinical trial; Immune system; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003136478,0.00104192,0.00227931,0.0002192661,0.0004215725,0.0008948547,0.0006530741,0.0014536,0.003659045],"category_scores_gemma":[0.002037555,0.0004756901,0.001682422,0.0003033156,0.0008732541,0.000811531,0.0003618532,0.001982891,0.0005093871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000531958,"about_ca_system_score_gemma":0.001475155,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000492962,"about_ca_topic_score_gemma":0.0009760807,"domain_scores_codex":[0.9991623,0.000465153,0.00006867815,0.0001208327,0.00006692797,0.0001160391],"domain_scores_gemma":[0.9985991,0.0003160216,0.0005273115,0.0001160808,0.00009482844,0.0003465311],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9732239,0.009012543,0.001872909,0.000468075,0.0006388714,0.00003392124,0.00006396652,0.0001877968,0.004412317,0.00003472327,0.000280933,0.009769929],"study_design_scores_gemma":[0.7712421,0.2221452,0.004636736,0.00003710142,0.0004602087,0.00004771182,0.00002417901,0.0002679318,0.0006679281,0.0000648718,0.0003949196,0.00001101028],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943653,0.001912851,0.0002939205,0.0002342646,0.0001204888,0.00232053,0.0003417464,0.00003916708,0.0003717615],"genre_scores_gemma":[0.991504,0.001580964,0.001091681,0.0004842997,0.0002551537,0.004023321,0.00039982,0.00001004849,0.0006507277],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003659045,"threshold_uncertainty_score":0.01658744,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01905269099969548,"score_gpt":0.3618134567543754,"score_spread":0.3427607657546799,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}