{"id":"W2922070393","doi":"10.1039/c9md00031c","title":"Tridecaptin-inspired antimicrobial peptides with activity against multidrug-resistant Gram-negative bacteria","year":2019,"lang":"en","type":"article","venue":"MedChemComm","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Queen's University Belfast; Royal Society; Queen's University; Wellcome Trust","keywords":"Antimicrobial; Multiple drug resistance; Gram-negative bacteria; Microbiology; Gram; Bacteria; Biology; Antimicrobial peptides; Antibiotics; Genetics; Escherichia coli; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009787972,0.0003414094,0.0001938703,0.000136108,0.0001230845,0.0002577849,0.0001702631,0.0003182243,0.001545974],"category_scores_gemma":[0.0001409559,0.00007759077,0.0001387915,0.0001750831,0.0001543694,0.0003320837,0.0002361727,0.0005597384,0.0005452629],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002282741,"about_ca_system_score_gemma":0.0001443956,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001316214,"about_ca_topic_score_gemma":0.0002543692,"domain_scores_codex":[0.9999101,0.00001454097,0.000009708123,0.00002233076,0.00002204224,0.00002131206],"domain_scores_gemma":[0.9998772,0.00001407258,0.00005094472,0.00001026432,0.00001433325,0.00003327177],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002370136,0.00006699201,0.0002110577,0.0002274022,0.00001553323,0.00016949,0.00004510371,0.0004537231,0.9805218,0.0007597683,0.0003511056,0.01694107],"study_design_scores_gemma":[0.00003317687,0.0008643427,0.0009543245,0.00001971112,0.00001701416,0.0007561643,0.00002298206,0.0006224705,0.9796788,0.000131474,0.01688321,0.00001633949],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9518164,0.01816162,0.01557265,0.0004841867,0.0003093773,0.0001196122,0.0006486853,0.000327793,0.01255967],"genre_scores_gemma":[0.9754369,0.004909793,0.01244834,0.000308297,0.00003576002,0.00006059865,0.0004181048,0.00003665144,0.006345581],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001545974,"threshold_uncertainty_score":0.005171776,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009280752773765107,"score_gpt":0.2110445857607855,"score_spread":0.2017638329870204,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}