{"id":"W2922097796","doi":"10.3389/fpls.2019.00270","title":"Plant-Produced Chimeric VHH-sIgA Against Enterohemorrhagic E. coli Intimin Shows Cross-Serotype Inhibition of Bacterial Adhesion to Epithelial Cells","year":2019,"lang":"en","type":"article","venue":"Frontiers in Plant Science","topic":"Transgenic Plants and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada; Western University; Agriculture and Agri-Food Canada","funders":"Agriculture and Agri-Food Canada; Uniformed Services University of the Health Sciences","keywords":"Intimin; Microbiology; Serotype; Biology; Escherichia coli; Adhesion; Chemistry; Enterobacteriaceae; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002912105,0.0001463194,0.0001937489,0.0001406095,0.0000763706,0.00003860507,0.0003821788,0.00009252756,0.00002136605],"category_scores_gemma":[0.00002341361,0.0001366307,0.00004547585,0.0002902357,0.0001738816,0.0000192836,0.00009657415,0.00008571029,0.00002513106],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002820279,"about_ca_system_score_gemma":0.0001288814,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001619994,"about_ca_topic_score_gemma":0.00001607508,"domain_scores_codex":[0.9985945,0.000024402,0.000286077,0.0005477624,0.0002240386,0.0003232007],"domain_scores_gemma":[0.9994029,0.000006769093,0.000102801,0.0003408468,0.00004351155,0.0001031259],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002812067,0.00006190479,0.007455481,0.00001775457,0.000004530446,0.000001742761,0.00007281986,0.0001908286,0.9887124,0.00001131982,0.002550105,0.0006399268],"study_design_scores_gemma":[0.0005079555,0.0001643589,0.01095586,0.00003124919,0.000004451575,0.000004893093,0.00004157903,0.0003764292,0.9835821,0.00001116169,0.004142535,0.0001774526],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957147,0.00002670246,0.0009110208,0.00003135901,0.001291522,0.0004787065,0.001235371,0.000009487155,0.0003010797],"genre_scores_gemma":[0.9966367,0.00006356317,0.002419784,0.0001406422,0.000103779,0.00002164848,0.0004400018,0.000008837578,0.0001650665],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005130301,"threshold_uncertainty_score":0.557164,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008517599395075962,"score_gpt":0.2292543605997788,"score_spread":0.2207367612047028,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}