{"id":"W2922097796","doi":"10.3389/fpls.2019.00270","title":"Plant-Produced Chimeric VHH-sIgA Against Enterohemorrhagic E. coli Intimin Shows Cross-Serotype Inhibition of Bacterial Adhesion to Epithelial Cells","year":2019,"lang":"en","type":"article","venue":"Frontiers in Plant Science","topic":"Transgenic Plants and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada; Western University; Agriculture and Agri-Food Canada","funders":"Agriculture and Agri-Food Canada; Uniformed Services University of the Health Sciences","keywords":"Intimin; Microbiology; Serotype; Biology; Escherichia coli; Adhesion; Chemistry; Enterobacteriaceae; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001207782,0.0003397483,0.0001411554,0.000116605,0.00008090767,0.0001633926,0.0002253025,0.0002610579,0.0006285156],"category_scores_gemma":[0.00007660969,0.00008548032,0.0002681771,0.00008239527,0.0001317822,0.00008217525,0.0001571203,0.0005085323,0.0002223146],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002125373,"about_ca_system_score_gemma":0.00008916014,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005475385,"about_ca_topic_score_gemma":0.0007040808,"domain_scores_codex":[0.9999061,0.0000143445,0.000007861224,0.00002191501,0.00002605767,0.00002370486],"domain_scores_gemma":[0.9999295,0.00001302297,0.00002114079,0.00001174256,0.00001038204,0.00001421996],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002160849,0.00001385927,0.0000468588,0.000009795554,0.000002493875,0.00001053576,0.000004498803,0.00002299409,0.9995335,0.00002062132,0.000007680549,0.0003056251],"study_design_scores_gemma":[0.000006607672,0.0003861083,0.002404232,0.000002701007,0.00001382737,0.0001335467,0.00001427595,0.0006576071,0.9947149,0.00001821438,0.001645822,0.000002131397],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947838,0.000503798,0.003632369,0.00006121125,0.00002161954,0.00001396707,0.0001258156,0.00006944835,0.0007879577],"genre_scores_gemma":[0.9954031,0.0002566217,0.002100527,0.0000466677,0.000004919448,0.00001010937,0.0003979816,0.00001476757,0.001765289],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006285156,"threshold_uncertainty_score":0.002102554,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008517599395075962,"score_gpt":0.2292543605997788,"score_spread":0.2207367612047028,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}