{"id":"W2922099376","doi":"10.1111/jdv.15400","title":"Efficacy of tildrakizumab for moderate‐to‐severe plaque psoriasis: pooled analysis of three randomized controlled trials at weeks 12 and 28","year":2019,"lang":"en","type":"article","venue":"Journal of the European Academy of Dermatology and Venereology","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University; Probity Medical Research","funders":"Merck","keywords":"Medicine; Placebo; Psoriasis; Internal medicine; Psoriasis Area and Severity Index; Randomized controlled trial; Gastroenterology; Dermatology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003555908,0.0002936833,0.005734343,0.0006077238,0.0001042431,0.000003892453,0.0004137217,0.0004261144,0.00008572488],"category_scores_gemma":[0.001347795,0.0001684026,0.001430446,0.000192669,0.0005334851,0.00005850594,0.0001593668,0.0002805643,0.000005637316],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001596828,"about_ca_system_score_gemma":0.00005559585,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005199985,"about_ca_topic_score_gemma":0.000007242878,"domain_scores_codex":[0.9915693,0.005461135,0.00235534,0.0002593344,0.00007207338,0.0002828627],"domain_scores_gemma":[0.9904027,0.005934779,0.003274478,0.000206035,0.0001320097,0.00005001588],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7556192,0.0004392367,0.04822745,0.0001910407,0.07817003,0.00001410764,0.00116144,0.0007644583,0.1026523,0.00457715,0.001181991,0.007001622],"study_design_scores_gemma":[0.7584872,0.000460584,0.07402788,0.0002591177,0.05753673,0.002042856,0.0001256478,0.0002176683,0.1030922,0.001990879,0.001316762,0.0004424606],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9849404,0.01092343,0.0001671919,0.00192126,0.0004872252,0.001105059,0.00006681433,0.000005874871,0.0003827101],"genre_scores_gemma":[0.9984499,0.0007651343,0.0001918683,0.0001604483,0.00004457153,0.00001196986,0.00001016214,0.00001926597,0.0003466982],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02580044,"threshold_uncertainty_score":0.686726,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02369100495985317,"score_gpt":0.2694269263587729,"score_spread":0.2457359213989197,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}