{"id":"W2922099849","doi":"10.1007/s12640-019-0002-z","title":"Impaired Spatial Cognition in Adult Rats Treated with Multiple Intracerebroventricular (ICV) Infusions of the Enteric Bacterial Metabolite, Propionic Acid, and Return to Baseline After 1 Week of No Treatment: Contribution to a Rodent Model of ASD","year":2019,"lang":"en","type":"article","venue":"Neurotoxicity Research","topic":"Autism Spectrum Disorder Research","field":"Neuroscience","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Morris water navigation task; Spatial learning; Saline; Metabolite; Neurochemistry; Water maze; Endocrinology; Internal medicine; Medicine; Neurochemical; Perseveration; Anesthesia; Psychology; Cognition; Pharmacology; Neurology; Neuroscience; Hippocampus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001756781,0.001402446,0.001010091,0.0008286767,0.0003429526,0.0005118747,0.0006139354,0.0008675779,0.002128017],"category_scores_gemma":[0.0002566387,0.0003709677,0.0003537079,0.0002498297,0.001300967,0.0007076336,0.0003429264,0.002391246,0.0003711179],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008160713,"about_ca_system_score_gemma":0.001191911,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007385137,"about_ca_topic_score_gemma":0.01150015,"domain_scores_codex":[0.9997525,0.00001465544,0.00001882754,0.00007936299,0.00004932001,0.00008533004],"domain_scores_gemma":[0.9994864,0.00002553447,0.000129088,0.00006122289,0.00006581525,0.0002320106],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00827543,0.001303395,0.001073822,0.00009221964,0.00004055999,0.000372725,0.000157094,0.0001397043,0.9837819,0.0001495936,0.0002435352,0.004370066],"study_design_scores_gemma":[0.0003710346,0.01308443,0.02847189,0.00003057476,0.0001218456,0.0005638477,0.0007120756,0.001284799,0.9535594,0.0003604121,0.001388481,0.00005130397],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975326,0.0003362687,0.0006072934,0.0001774165,0.0001144974,0.00002315371,0.0004256343,0.00009487707,0.0006882806],"genre_scores_gemma":[0.9926658,0.0005360165,0.00109697,0.0001012675,0.00001882864,0.0001035142,0.0005394032,0.00003143754,0.004906756],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007385137,"threshold_uncertainty_score":0.01468432,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02879230929122312,"score_gpt":0.2875437242376636,"score_spread":0.2587514149464405,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}