{"id":"W2922099849","doi":"10.1007/s12640-019-0002-z","title":"Impaired Spatial Cognition in Adult Rats Treated with Multiple Intracerebroventricular (ICV) Infusions of the Enteric Bacterial Metabolite, Propionic Acid, and Return to Baseline After 1 Week of No Treatment: Contribution to a Rodent Model of ASD","year":2019,"lang":"en","type":"article","venue":"Neurotoxicity Research","topic":"Autism Spectrum Disorder Research","field":"Neuroscience","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Morris water navigation task; Spatial learning; Saline; Metabolite; Neurochemistry; Water maze; Endocrinology; Internal medicine; Medicine; Neurochemical; Perseveration; Anesthesia; Psychology; Cognition; Pharmacology; Neurology; Neuroscience; Hippocampus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005761712,0.000223924,0.000481999,0.0005413545,0.00009048387,0.00003911764,0.0003504138,0.00009857246,0.00009560731],"category_scores_gemma":[0.00206631,0.0001506559,0.00008982648,0.001526942,0.0002306155,0.0001766808,0.0004228324,0.0003454311,0.00001583549],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001429704,"about_ca_system_score_gemma":0.0002606574,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001201033,"about_ca_topic_score_gemma":0.001084079,"domain_scores_codex":[0.9956943,0.001318934,0.0005567161,0.0006361516,0.001191853,0.0006020765],"domain_scores_gemma":[0.998316,0.0003569883,0.000158081,0.0005710479,0.0004058728,0.0001919647],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007306655,0.001180326,0.04300299,0.00009546872,0.00001019413,0.000009248497,0.0003429487,0.0003293014,0.9473343,0.00005712493,0.000002504293,0.0003289326],"study_design_scores_gemma":[0.003437694,0.003047029,0.07870553,0.0001623235,0.00001552705,0.000005917454,0.0000174062,0.04913729,0.8653062,0.00004161059,0.000009845636,0.0001136397],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912976,0.0000117813,0.000176227,0.0006398449,0.00003326752,0.007237137,0.0005657364,0.00001473411,0.00002367825],"genre_scores_gemma":[0.9990343,0.00006225479,0.00006492351,0.00004546099,0.0000173778,0.0006665071,0.00001662747,0.00002771395,0.00006477259],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08202812,"threshold_uncertainty_score":0.6143571,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02879230929122312,"score_gpt":0.2875437242376636,"score_spread":0.2587514149464405,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}