{"id":"W2922125039","doi":"10.1158/0008-5472.can-18-2565","title":"Myc and Loss of p53 Cooperate to Drive Formation of Choroid Plexus Carcinoma","year":2019,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"National Cancer Institute; Brain Tumour Charity; Cancer Research UK; California Institute for Regenerative Medicine","keywords":"Choroid plexus; Carcinoma; Medicine; Anatomy; Internal medicine; Central nervous system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001619104,0.0003434385,0.0001737117,0.0006012904,0.0002244761,0.0003411051,0.0002164838,0.0003581507,0.00135433],"category_scores_gemma":[0.00019347,0.0001995327,0.000228302,0.0001994241,0.0004095766,0.0001905014,0.0003251146,0.0007100655,0.0003413492],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006043259,"about_ca_system_score_gemma":0.0003567441,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001782526,"about_ca_topic_score_gemma":0.001894678,"domain_scores_codex":[0.9997805,0.00003992279,0.00001844799,0.00004134656,0.00006987256,0.00004989649],"domain_scores_gemma":[0.9997573,0.00005419808,0.0000731302,0.00003362932,0.00001546381,0.00006619281],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006696358,0.00003015089,0.000481805,0.00001400869,0.000004274788,0.0001732189,0.00001274189,0.0001088693,0.9982991,0.0002059013,0.0000567761,0.0005461211],"study_design_scores_gemma":[0.00002155437,0.000270629,0.004927715,0.000005800389,0.00001012594,0.000912746,0.00004513543,0.001562637,0.9900394,0.00008084626,0.002119592,0.000003820377],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939083,0.0007529514,0.002577783,0.0001307745,0.00002412839,0.00004998051,0.0005287504,0.0001273847,0.001899831],"genre_scores_gemma":[0.9961682,0.0003695147,0.001404556,0.00002766348,0.000002874177,0.000043615,0.000291059,0.00001885156,0.001673612],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001782526,"threshold_uncertainty_score":0.004530728,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04535723781499659,"score_gpt":0.369028638054103,"score_spread":0.3236714002391065,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}