{"id":"W2922197312","doi":"10.1161/atvb.38.suppl_1.125","title":"Abstract 125: Intensive Statin Therapy Negatively Modulates AdipoR Activity in the Monocyte-macrophage Lineage <i>in vivo</i> and <i>in vitro</i>","year":2018,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Cancer, Lipids, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Rosuvastatin; Statin; Atorvastatin; Medicine; Internal medicine; Endocrinology; Inflammation; Monocyte; Adiponectin; Pharmacology; Insulin resistance; Diabetes mellitus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001463387,0.0003792849,0.0005622534,0.0001673402,0.0001815602,0.0004818947,0.0001719974,0.0003188958,0.007498282],"category_scores_gemma":[0.000186447,0.000145747,0.0004396721,0.0002497549,0.000260496,0.0001762349,0.0002258156,0.0007037927,0.001630978],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001994931,"about_ca_system_score_gemma":0.0003524863,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008301119,"about_ca_topic_score_gemma":0.0007892535,"domain_scores_codex":[0.9997615,0.0000376719,0.00003131144,0.00003681517,0.00005321727,0.00007936431],"domain_scores_gemma":[0.9998629,0.00002218063,0.0000356285,0.00001502277,0.00002341691,0.00004083445],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005936394,0.000348579,0.001302525,0.0003865478,0.00004627741,0.0001373385,0.00003869046,0.00005585418,0.9827727,0.00007201371,0.0008945818,0.008008517],"study_design_scores_gemma":[0.0007719695,0.009630813,0.05683734,0.00009226871,0.0002521891,0.00079911,0.0001962953,0.0008923877,0.9208272,0.000124384,0.009552166,0.0000238488],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9835384,0.006643896,0.001583753,0.0005293717,0.0003334303,0.00009281383,0.002167989,0.0001358444,0.004974416],"genre_scores_gemma":[0.9812132,0.00341656,0.001087551,0.0005715431,0.0001782079,0.0002069244,0.003697247,0.0000368599,0.009591992],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.007498282,"threshold_uncertainty_score":0.02508432,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02662554298259938,"score_gpt":0.2823065530745402,"score_spread":0.2556810100919408,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}