{"id":"W2922207925","doi":"10.1074/jbc.h119.007830","title":"Let's get this pyrin started!","year":2019,"lang":"en","type":"review","venue":"Journal of Biological Chemistry","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"Wellcome Trust","keywords":"Inflammasome; Pyrin domain; Iron homeostasis; Biology; Homeostasis; Gut flora; Cell biology; Inflammation; Computational biology; Biochemistry; Immunology; Metabolism","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005214136,0.0007190069,0.0007551652,0.001101197,0.0005100298,0.001466847,0.0005902253,0.001704461,0.01612789],"category_scores_gemma":[0.001062756,0.0001989688,0.0005625766,0.0007196122,0.0006886894,0.002979362,0.001028521,0.003474213,0.01218036],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000507422,"about_ca_system_score_gemma":0.000621079,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006573873,"about_ca_topic_score_gemma":0.0009882584,"domain_scores_codex":[0.9997519,0.00005345649,0.00003100443,0.00003980903,0.00008916211,0.00003477932],"domain_scores_gemma":[0.9997335,0.00008581399,0.00003296164,0.00001717174,0.00008211481,0.00004832661],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002198304,0.00007609395,0.0001446757,0.005280111,0.00005571795,0.0003182095,0.00009798062,0.00009803119,0.002867418,0.007351604,0.1702807,0.8132097],"study_design_scores_gemma":[0.000008102165,0.00004941444,0.0001403366,0.0005485877,0.00001040198,0.0004609472,0.00002864939,0.00001568725,0.0004041479,0.001096563,0.9972307,0.000006600937],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004355266,0.9658279,0.0009625845,0.01077341,0.01150768,0.00002898605,0.000103557,0.0001336882,0.01022665],"genre_scores_gemma":[0.003284225,0.9530835,0.001278874,0.007553216,0.002724207,0.00002841177,0.0002009541,0.00004516186,0.03180155],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01612789,"threshold_uncertainty_score":0.05395317,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03911552948300134,"score_gpt":0.3015813685966912,"score_spread":0.2624658391136898,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}