{"id":"W2922227428","doi":"10.1186/s13023-018-0993-1","title":"Incidental screen positive findings in a prospective cohort study in Matlab, Bangladesh: insights into expanded newborn screening for low-resource settings","year":2019,"lang":"en","type":"article","venue":"Orphanet Journal of Rare Diseases","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Newborn Screening Ontario; Children's Hospital of Eastern Ontario; Ottawa Hospital","funders":"International Centre for Diarrhoeal Disease Research, Bangladesh; Bill and Melinda Gates Foundation","keywords":"Medicine; Cord blood; Newborn screening; Cohort; Umbilical cord; Pediatrics; Cohort study; Heel; Obstetrics; Cord; Prospective cohort study; Dried blood spot; Surgery; Internal medicine; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001028161,0.0002733076,0.0002515659,0.0008935844,0.00101005,0.0009144599,0.0006518277,0.000322677,0.001790428],"category_scores_gemma":[0.003083143,0.0002342716,0.0002894764,0.00134651,0.0005157251,0.0003442683,0.0007136386,0.0005035868,0.0001823995],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002037891,"about_ca_system_score_gemma":0.002763114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.4192902,"about_ca_topic_score_gemma":0.5081945,"domain_scores_codex":[0.9992597,0.0001769907,0.00007680198,0.0001430519,0.0001606617,0.0001827565],"domain_scores_gemma":[0.9985649,0.0002102463,0.0004694065,0.0001322444,0.000283113,0.0003401516],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00001297138,0.00001085342,0.9981986,0.00001140192,0.00001085498,0.0001895205,0.0005419466,0.00001113258,0.0001389229,0.00003249254,0.00009550598,0.0007458357],"study_design_scores_gemma":[0.000001323901,0.00002291213,0.9975775,0.000022498,0.000009515894,0.0002154742,0.001855932,0.00005056078,0.00002531394,0.00001762282,0.000197587,0.000003771515],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980957,0.0001758132,0.00008383568,0.0001871729,0.000004853104,0.0000307422,0.0007029544,0.000002208283,0.0007166498],"genre_scores_gemma":[0.999104,0.0002293263,0.0001486281,0.00006117122,0.000002847091,0.00001688023,0.0002778535,0.000001992268,0.0001572078],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4192902,"threshold_uncertainty_score":0.8336994,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004342241176757935,"score_gpt":0.2421238186442853,"score_spread":0.2377815774675274,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}