{"id":"W2922230818","doi":"10.1038/s41598-019-39426-5","title":"Trophoblast-Specific Expression of Hif-1α Results in Preeclampsia-Like Symptoms and Fetal Growth Restriction","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":107,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Canadian Institutes of Health Research; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Trophoblast; Preeclampsia; Placenta; Fetus; Placentation; Intrauterine growth restriction; Biology; Hypoxia (environmental); Pregnancy; Spiral artery; Placental insufficiency; Andrology; Pathophysiology; Endocrinology; Internal medicine; Medicine; Chemistry; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002279181,0.0004292394,0.0003757082,0.0004507564,0.0001691335,0.0002788398,0.0002290352,0.0005045136,0.00145019],"category_scores_gemma":[0.0002714034,0.0002749429,0.0003922689,0.0002919426,0.0005091218,0.0001867067,0.0002530512,0.000910007,0.0002766597],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003835542,"about_ca_system_score_gemma":0.0002794072,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006946778,"about_ca_topic_score_gemma":0.0005070599,"domain_scores_codex":[0.9997298,0.00004744842,0.00004163084,0.00007131798,0.00006534265,0.00004445908],"domain_scores_gemma":[0.9996932,0.00003986117,0.000117786,0.00003805524,0.00001324189,0.00009799692],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003349927,0.00007985821,0.000284171,0.00002979735,0.00001075847,0.0004591714,0.00003216124,0.00009368122,0.9974694,0.0002769041,0.00006273059,0.0008664478],"study_design_scores_gemma":[0.0001727855,0.002578218,0.01447566,0.00002322781,0.00009031902,0.00527563,0.0001181668,0.002507812,0.9690225,0.0004605828,0.005255245,0.00001983353],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887834,0.001281823,0.006828909,0.0003000734,0.0001006746,0.00007224833,0.0007567102,0.000331378,0.001544701],"genre_scores_gemma":[0.9921845,0.001239467,0.002293485,0.0001176671,0.0000251731,0.00009655038,0.0005835746,0.00005560758,0.003403943],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00145019,"threshold_uncertainty_score":0.004851341,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01163259978293421,"score_gpt":0.232357664229034,"score_spread":0.2207250644460997,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}