{"id":"W2922244516","doi":"10.1371/journal.pbio.2006966","title":"Environment-induced same-sex mating in the yeast Candida albicans through the Hsf1–Hsp90 pathway","year":2019,"lang":"en","type":"article","venue":"PLoS Biology","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Natural Science Foundation of China","keywords":"Biology; Mating of yeast; Schizosaccharomyces pombe; Mating type; Candida albicans; Saccharomyces cerevisiae; Mating; Schizosaccharomyces; Homothallism; Heterothallic; Sexual reproduction; Genetics; Cell biology; Yeast; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006408316,0.0003190922,0.0001301615,0.0001889806,0.0001975034,0.0002836956,0.0001716658,0.000148689,0.0006534841],"category_scores_gemma":[0.00004854462,0.00007992893,0.0002754091,0.0001344398,0.0001070774,0.0001264114,0.0002717506,0.0003432287,0.0002146803],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002299158,"about_ca_system_score_gemma":0.0002471461,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006777553,"about_ca_topic_score_gemma":0.001242553,"domain_scores_codex":[0.9999315,0.000008856715,0.000006592406,0.00001266038,0.00001993056,0.00002060238],"domain_scores_gemma":[0.999944,0.000004813004,0.00001634275,0.000008126659,0.000007574301,0.00001915925],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005264419,0.00002379839,0.0002649105,0.00002545422,0.000003737287,0.00006690669,0.000007049507,0.00005115107,0.9982018,0.00007342974,0.00005064191,0.001178524],"study_design_scores_gemma":[0.000009573147,0.0001535112,0.01813818,0.000006973605,0.00001217967,0.0003490199,0.00004887045,0.0008532803,0.9787024,0.00007805284,0.001638199,0.000009827047],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955621,0.001392179,0.001146108,0.00007968187,0.00002800556,0.00001954425,0.0004963117,0.00008132331,0.001194775],"genre_scores_gemma":[0.9966766,0.0006684777,0.0008528074,0.00006150777,0.000005074091,0.00001608172,0.0005876951,0.0000105299,0.001121245],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006777553,"threshold_uncertainty_score":0.00218612,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03336279706811388,"score_gpt":0.2720032780001884,"score_spread":0.2386404809320745,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}