{"id":"W2922270019","doi":"10.3389/fimmu.2019.00465","title":"Circulating LPS and (1→3)-β-D-Glucan: A Folie à Deux Contributing to HIV-Associated Immune Activation","year":2019,"lang":"fr","type":"review","venue":"Frontiers in Immunology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; McGill University; McGill University Health Centre","funders":"Fonds de Recherche du Québec - Santé; Canadian HIV Trials Network, Canadian Institutes of Health Research; McGill University; Canadian Institutes of Health Research; Canadian Foundation for AIDS Research; Styrelsen för Internationellt Utvecklingssamarbete","keywords":"Immune system; Immunology; Innate immune system; Microbiome; Lipopolysaccharide; Context (archaeology); Biology; Immune Dysfunction; T cell; Immune dysregulation; Bioinformatics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004884916,0.0007678984,0.0009264956,0.001650842,0.0002333603,0.001060135,0.0006599959,0.00123305,0.002931768],"category_scores_gemma":[0.0007517611,0.0002297121,0.0002900364,0.001469349,0.0005614421,0.001271064,0.0006506674,0.001948897,0.002217514],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006604003,"about_ca_system_score_gemma":0.001016097,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008352275,"about_ca_topic_score_gemma":0.001031922,"domain_scores_codex":[0.9998475,0.00002716896,0.00002139805,0.00003170641,0.00005338222,0.00001873129],"domain_scores_gemma":[0.9997198,0.0001115037,0.00004144859,0.000008522921,0.00008168232,0.00003708503],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000122023,0.00004491107,0.000199915,0.01063149,0.00005235656,0.0001625907,0.00004894962,0.0001607611,0.001744104,0.00406742,0.03903132,0.9437341],"study_design_scores_gemma":[0.00001255149,0.00008767458,0.0009175778,0.002698257,0.0000523768,0.001021195,0.00005349391,0.00005724474,0.000488223,0.002054297,0.992542,0.00001513552],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007561352,0.9985215,0.00008468103,0.000390497,0.0003632646,0.000002381191,0.00001116491,0.000005071195,0.0005458164],"genre_scores_gemma":[0.0005824807,0.9980366,0.0001050729,0.0002503976,0.0004089877,0.000004438736,0.00002232534,0.000001390488,0.0005883877],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002931768,"threshold_uncertainty_score":0.009807765,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02097775795527945,"score_gpt":0.2836765883889288,"score_spread":0.2626988304336494,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}