{"id":"W2922279044","doi":"10.1161/atvb.38.suppl_1.680","title":"Abstract 680: Specific Deletion of SHP-1 in Smooth Muscle Cells Restores PDGF Action in Diabetes","year":2018,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Atherosclerosis and Cardiovascular Diseases","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Platelet-derived growth factor receptor; Internal medicine; Protein tyrosine phosphatase; Endocrinology; Platelet-derived growth factor; Medicine; Hypoxia (environmental); Ligation; Tyrosine phosphorylation; In vivo; Diabetes mellitus; Vascular smooth muscle; Growth factor; Chemistry; Receptor; Biology; Smooth muscle; Oxygen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001060888,0.0003947927,0.000244268,0.0002301731,0.0001357203,0.0001780369,0.0001838237,0.0002402165,0.002587342],"category_scores_gemma":[0.00005793344,0.0001404777,0.0002108008,0.0001378254,0.0001854576,0.0001256313,0.0001811433,0.0006746157,0.0006938746],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001509199,"about_ca_system_score_gemma":0.0001563406,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003841501,"about_ca_topic_score_gemma":0.0004171477,"domain_scores_codex":[0.9998863,0.00001314876,0.00001372989,0.00001861573,0.00003058188,0.0000375786],"domain_scores_gemma":[0.9998809,0.00001257428,0.00003324585,0.000009579471,0.000009155714,0.00005449005],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002394794,0.00006134715,0.0001465853,0.00003534187,0.000003041769,0.00003882452,0.000006609286,0.00001538531,0.9984663,0.00002129188,0.00004964255,0.0009161836],"study_design_scores_gemma":[0.00008458718,0.001394665,0.007759765,0.00001647885,0.00002859895,0.0002611217,0.00002842558,0.0003102737,0.9869525,0.00003218433,0.003127142,0.000004202072],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960902,0.00117646,0.0008087778,0.0001191466,0.00007374256,0.00002179485,0.0005726152,0.0000628147,0.001074353],"genre_scores_gemma":[0.9896521,0.001561903,0.001153212,0.0001223853,0.00004938319,0.00007018459,0.001842893,0.00002813415,0.005519688],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002587342,"threshold_uncertainty_score":0.008655548,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03655933953957283,"score_gpt":0.2642549671379335,"score_spread":0.2276956275983607,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}